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Substance P(1-7) TFA
🥰Excellent
Catalog No. T75963Cas No. 2828433-22-1
Substance P(1-7) TFA is a fragment of neuropeptide P (SP) with anti-nociceptive activity. It prevents morphine-induced spontaneous pain behavior through the spinal NMDA-NO cascade, and can be used in research on neurological diseases.
Substance P(1-7) TFA
🥰Excellent
Purity: 98.23%
Catalog No. T75963Cas No. 2828433-22-1
Substance P(1-7) TFA is a fragment of neuropeptide P (SP) with anti-nociceptive activity. It prevents morphine-induced spontaneous pain behavior through the spinal NMDA-NO cascade, and can be used in research on neurological diseases.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $57 | In Stock | |
| 5 mg | $89 | In Stock | |
| 10 mg | $147 | In Stock | |
| 25 mg | $289 | In Stock | |
| 50 mg | $497 | In Stock | |
| 100 mg | $719 | In Stock | |
| 200 mg | $987 | In Stock |
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Purity:98.23%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Substance P(1-7) TFA is a fragment of neuropeptide P (SP) with anti-nociceptive activity. It prevents morphine-induced spontaneous pain behavior through the spinal NMDA-NO cascade, and can be used in research on neurological diseases. |
| In vivo | Injection of low doses of Substance P(1-7) TFA (1.0-4.0 pM) and concomitant administration of SP or SP(5-11) (0.1 nM) significantly inhibited aversive behaviors triggered by SP or SP(5-11). These findings suggest that endogenously generated Substance P(1-7) may play an important function in the spinal cord by modulating the action of SP or SP(5-11). [1] |
| Molecular Weight | 1014.06 |
| Formula | C43H66F3N13O12 |
| Cas No. | 2828433-22-1 |
| Smiles | C(C(O)=O)(F)(F)F.C([C@@H](NC(=O)[C@H]1N(C([C@H](CCCNC(=N)N)N)=O)CCC1)CCCCN)(=O)N2[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=CC=C3)C(O)=O)=O)CCC(N)=O)=O)CCC(N)=O)=O)CCC2 |
Storage & Solubility Information
| Storage | keep away from moisture,keep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | H2O: 40 mg/mL (39.45 mM), Sonication is recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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