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Product Introduction

Bioactivity

Description	N-Acetyl-L-tryptophan (N-acetyltryptophan) is an inhibitor of neurokinin 1 receptor (NK1-receptor, NK1R).
Alias	N-acetyltryptophan

Chemical Properties

Molecular Weight	246.26
Formula	C₁₃H₁₄N₂O₃
Cas No.	1218-34-4

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 25 mg/mL (101.52 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.0607 mL	20.3037 mL	40.6075 mL	203.0374 mL
5 mM	0.8121 mL	4.0607 mL	8.1215 mL	40.6075 mL
10 mM	0.4061 mL	2.0304 mL	4.0607 mL	20.3037 mL
20 mM	0.2030 mL	1.0152 mL	2.0304 mL	10.1519 mL
50 mM	0.0812 mL	0.4061 mL	0.8121 mL	4.0607 mL
100 mM	0.0406 mL	0.2030 mL	0.4061 mL	2.0304 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

NAcetylLtryptophanEndogenous MetaboliteN-Acetyl-L-tryptophanN Acetyl L tryptophaninhibitInhibitor