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[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P

Catalog No. TP1931Cas No. 96736-12-8

Broad spectrum neuropeptide inverse agonist and antagonist. Potent full inverse agonist for the ghrelin receptor (EC50 = 5.2 nM); diminishes constitutive ghrelin receptor signaling. Also antagonist at tachykinin, bradykinin, CCK and bombesin receptors. Induces apoptosis and inhibits cancer cell growth in vitro.

[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P
Other Forms of [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P:
[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetateTP1931L1
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[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P

Catalog No. TP1931Cas No. 96736-12-8
Broad spectrum neuropeptide inverse agonist and antagonist. Potent full inverse agonist for the ghrelin receptor (EC50 = 5.2 nM); diminishes constitutive ghrelin receptor signaling. Also antagonist at tachykinin, bradykinin, CCK and bombesin receptors. Induces apoptosis and inhibits cancer cell growth in vitro.
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Product Introduction

Bioactivity
Description
Broad spectrum neuropeptide inverse agonist and antagonist. Potent full inverse agonist for the ghrelin receptor (EC50 = 5.2 nM); diminishes constitutive ghrelin receptor signaling. Also antagonist at tachykinin, bradykinin, CCK and bombesin receptors. In
Chemical Properties
Molecular Weight1516.85
FormulaC79H109N19O12
Cas No.96736-12-8
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 1 mg/mL

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Keywords

[DArg1,DPhe5,DTrp7,9,Leu11]Substance P[D Arg1,D Phe5,D Trp7,9,Leu11] Substance P[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P[D-Arg-1,D-Phe5,D-Trp7,9,Leu11]-Substance P
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