Shopping Cart
- Remove All
Your shopping cart is currently empty
Ac2-26 ammonium
🥰Excellent
Catalog No. T78371
Alias Ac2-26 ammonium (151988-33-9 free base)
Ac2-26 ammonium is an Annexin-A1 (AnxA1) N-terminal derived peptide with anti-inflammatory activity and alleviates liver ischemia-reperfusion injury in mice by regulating IL-22/IL-22R1/STAT3 signaling and eNOS pathways.
Ac2-26 ammonium
Ac2-26 ammonium
🥰Excellent
Catalog No. T78371Alias Ac2-26 ammonium (151988-33-9 free base)
Ac2-26 ammonium is an Annexin-A1 (AnxA1) N-terminal derived peptide with anti-inflammatory activity and alleviates liver ischemia-reperfusion injury in mice by regulating IL-22/IL-22R1/STAT3 signaling and eNOS pathways.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $52 | In Stock | |
| 5 mg | $123 | In Stock | |
| 10 mg | $197 | In Stock | |
| 25 mg | $348 | In Stock | |
| 50 mg | $538 | In Stock | |
| 100 mg | $766 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "Ac2-26 ammonium"
Diallyl disulfide
TN15762179-57-9
Diallyl disulfide has antitumor effect, the effect can be enhanced by miR-200b and miR-22.
- $30
Size
QTY
L-NAME hydrochloride
NG-Nitroarginine methyl ester hydrochloride, N(G)-Nitro-L-arginine methyl ester, L-NAME HCl
T657051298-62-5
L-NAME hydrochloride (L-NAME HCl), a cell-permeable NO synthase inhibitor, displays Ki values of 4.4 μM, 15 nM, and 39 nM, for iNOS (mouse) , nNOS (bovine) , and eNOS (human), respectively.
- $46
Size
QTY
Dexamethasone acetate
NSC 39471, Dexamethasone 21-acetate, Dexamethasone 17-acetate, Dexamethason acetate
T09471177-87-3
Dexamethasone acetate (NSC 39471) is the acetate salt form of Dexamethasone, a synthetic adrenal corticosteroid with potent anti-inflammatory properties. In addition to binding to specific nuclear steroid receptors, dexamethasone also interferes with NF-kB activation and apoptotic pathways. This agent lacks the salt-retaining properties of other related adrenal hormones.
- $45
Size
QTY
S-Methylisothiourea sulfate
(S)-Methylisothiourea sulfate
T22419867-44-7
S-Methylisothiourea sulfate ((S)-Methylisothiourea sulfate) is a potent and selective inhibitor of iNOS and exerts beneficial effects in rodent models of septic shock[1].
- $33
Size
QTY
Aminoguanidine hydrochloride
Cited
Pimagedine hydrochloride, Imino semicarbazide, Hydrazinecarboximidamide, Guanylhydrazine hydrochloride
T03581937-19-5
Aminoguanidine hydrochloride (Hydrazinecarboximidamide) is a diamine oxidase and NO synthase inhibitor, used in the treatment of diabetic nephropathy.
- $36
Size
QTY
CitedCannabigerol Cited
TN146525654-31-3
Cannabigerol is a high affinity α±2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist, and low affinity CB1 receptor antagonist ; also binds to the CB2 receptor; it can relieve interocular pressure, which may be of benefit in the treatment of glaucoma.
- $148
Size
QTY
CitedEIT hydrobromide
S-Ethylisothiourea hydrobromide, 2-Ethyl-2-thiopseudourea hydrobromide
T227611071-37-0
EIT hydrobromide (S-Ethylisothiourea hydrobromide) is an iNOS inhibitor.
- $29
Size
QTY
Miconazole Cited
R18134
T034422916-47-8
Miconazole (R18134) is an imidazole antifungal agent used both topically and via intravenous infusion.
- $39
Size
QTY
Cited1400W dihydrochloride Cited
N-(3-(Aminomethyl)benzyl)acetamidine, 1400W 2HCl
T3491214358-33-5
1400W dihydrochloride (N-(3-(Aminomethyl)benzyl)acetamidine) is a highly effective and specific inhibitor of inducible NOS2 (iNOS).
- $43
Size
QTY
CitedS-(2-aminoethyl) Isothiourea (dihydrobromide)
T754356-10-0
S-(2-aminoethyl) Isothiourea (dihydrobromide) is a non-selective inhibitor of all NOS isoforms. For human nNOS, eNOS, and iNOS, the Ki values are 1.8, 2.1, and 0.59 µM, respectively
- $38
Size
QTY
Flavone
2-Phenylchromone, 2-Phenyl-4-chromone, 2-Phenyl-4-benzopyron
T2876525-82-6
Flavone (2-Phenyl-4-chromone) have effects on CYP (P450) activity which are enzymes that metabolize most drugs in the body.
- $42
Size
QTY
3-Bromo-7-nitroindazole
T1010774209-34-0
3-Bromo-7-nitroindazole is a specific neuronal nitric oxide synthase (nNOS) inhibitor that affects the synthesis of the intercellular messenger NO throughout the brain and body.
- $44
Size
QTY
Select Batch
Contact us for more batch information
Resource Download
Product Introduction
Bioactivity
Chemical Properties
| Description | Ac2-26 ammonium is an Annexin-A1 (AnxA1) N-terminal derived peptide with anti-inflammatory activity and alleviates liver ischemia-reperfusion injury in mice by regulating IL-22/IL-22R1/STAT3 signaling and eNOS pathways. |
| Targets&IC50 | FPR1 (human):1.4 μM (EC50), FPR2 (human):1.8 μM (EC50) |
| In vitro | In radioligand binding assays, Ac2-26 ammonium was able to bind to HEK293 cells expressing human formyl peptide receptor 1 (FPR1) or FPR2, FPR1 (EC50=1.4 μM) and FPR2 (EC50=1.8 μM). Ac2-26 ammonium inhibited lipopolysaccharide (LPS)-induced prostaglandin (E2) and nitric oxide (NO) production in rat microglia. [1] |
| In vivo | In a rat model of ventilator-induced ischemia-reperfusion injury, Ac2-26 ammonium was able to reduce pulmonary edema when administered at a dose of 0.5-1 mg/kg. [2] |
| Alias | Ac2-26 ammonium (151988-33-9 free base) |
| Molecular Weight | 3089.43 (free base) |
| Formula | C141H210N32O44S.xNH3 |
Storage & Solubility Information
| Storage | keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | H2O: 30 mg/mL (130.18 mM), Sonication is recommended. Adjust pH to 8 and sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
H2O
| ||||||||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Ac2-26 ammonium | purchase Ac2-26 ammonium | Ac2-26 ammonium cost | order Ac2-26 ammonium | Ac2-26 ammonium in vivo | Ac2-26 ammonium in vitro | Ac2-26 ammonium formula | Ac2-26 ammonium molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.