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SU 10603 is a specific inhibitor of 17α-hydroxylase (also known as CYP17A1 and P450c17) used to study steroid hormone synthesis.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $293 | In Stock | |
5 mg | $722 | In Stock | |
10 mg | $987 | In Stock | |
25 mg | $1,520 | In Stock | |
50 mg | $1,980 | In Stock | |
100 mg | $2,760 | In Stock |
Description | SU 10603 is a specific inhibitor of 17α-hydroxylase (also known as CYP17A1 and P450c17) used to study steroid hormone synthesis. |
In vitro | Treatment of 661 W cells with SU 10603 (10 μM) prevents the conversion of pregnenolone to dehydroepiandrosterone (DHEA).[2] |
In vivo | Methods: NNC 05-711 (50, 100, 200 μg/10 μL, intrathecal injection, once a day) was used to treat rats with chronic sciatic nerve constriction injury (CCI) and its analgesic effect was observed. Results: NNC 05-711 exerted an effective analgesic effect in the CCI rat model. Compared with the CCI + saline group, the paw withdrawal threshold (WT) and paw withdrawal latency (WL) values increased after 1 day. [3] |
Alias | SU-10603, SU10603 |
Molecular Weight | 257.72 |
Formula | C15H12ClNO |
Cas No. | 786-97-0 |
Relative Density. | 1.275g/cm3 |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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