Powder: -20°C for 3 years | In solvent: -80°C for 1 year
pCPA methyl ester hydrochloride (4-Chloro-DL-phenylalanine methyl ester hydrochloride) is an inhibitor of tryptophan hydroxylase inhibitor and 5-HT synthesis. pCPA methyl ester hydrochloride is permeable across the blood-brain barrier and reduces 5-HT central availability.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 mg | Inquiry | $ 45.00 |
Description | pCPA methyl ester hydrochloride (4-Chloro-DL-phenylalanine methyl ester hydrochloride) is an inhibitor of tryptophan hydroxylase inhibitor and 5-HT synthesis. pCPA methyl ester hydrochloride is permeable across the blood-brain barrier and reduces 5-HT central availability. |
In vivo | In C57BL/6 elite male mice, 5-HT levels decreased by 85% and 55% in the hippocampus of mice treated with oral or i.p. PCPA methyl ester hydrochloride(250, 500 mg/kg), respectively, whereas in the prefrontal cortex, 5-HT levels decreased by 65% and 50%[4]. |
Synonyms | 4-Chloro-DL-phenylalanine methyl ester hydrochloride |
Molecular Weight | 250.12 |
Formula | C10H13Cl2NO2 |
CAS No. | 14173-40-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 45 mg/mL (179.91 mM), ultrasonic and warming and heat to 60°C
DMSO: 245 mg/mL (979.53 mM), sonification is recommended.
You can also refer to dose conversion for different animals. More
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pCPA methyl ester hydrochloride 14173-40-1 GPCR/G Protein Metabolism Neuroscience 5-HT Receptor Hydroxylase 5-HT Inhibitor PCPA methyl ester insomnia pCPA methyl ester Hydrochloride reversible 5-hydroxytryptamine Receptor BBB Serotonin Receptor 4-Chloro-DL-phenylalanine methyl ester hydrochloride inhibit Tryptophan Hydroxylase inhibitor