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pCPA methyl ester hydrochloride

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Catalog No. T41143Cas No. 14173-40-1
Alias 4-Chloro-DL-phenylalanine methyl ester hydrochloride

pCPA methyl ester hydrochloride (4-Chloro-DL-phenylalanine methyl ester hydrochloride) is an inhibitor of tryptophan hydroxylase inhibitor and 5-HT synthesis. pCPA methyl ester hydrochloride is permeable across the blood-brain barrier and reduces 5-HT central availability.

pCPA methyl ester hydrochloride

pCPA methyl ester hydrochloride

🥰Excellent
Purity: 99.08%
Catalog No. T41143Alias 4-Chloro-DL-phenylalanine methyl ester hydrochlorideCas No. 14173-40-1
pCPA methyl ester hydrochloride (4-Chloro-DL-phenylalanine methyl ester hydrochloride) is an inhibitor of tryptophan hydroxylase inhibitor and 5-HT synthesis. pCPA methyl ester hydrochloride is permeable across the blood-brain barrier and reduces 5-HT central availability.
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200 mg$29In Stock
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Purity:99.08%
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Product Introduction

Bioactivity
Description
pCPA methyl ester hydrochloride (4-Chloro-DL-phenylalanine methyl ester hydrochloride) is an inhibitor of tryptophan hydroxylase inhibitor and 5-HT synthesis. pCPA methyl ester hydrochloride is permeable across the blood-brain barrier and reduces 5-HT central availability.
In vivo
In C57BL/6 elite male mice, 5-HT levels decreased by 85% and 55% in the hippocampus of mice treated with oral or i.p. PCPA methyl ester hydrochloride(250, 500 mg/kg), respectively, whereas in the prefrontal cortex, 5-HT levels decreased by 65% and 50%[4].
Alias4-Chloro-DL-phenylalanine methyl ester hydrochloride
Chemical Properties
Molecular Weight250.12
FormulaC10H13Cl2NO2
Cas No.14173-40-1
SmilesCl.COC(=O)[C@@H](N)Cc1ccc(Cl)cc1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 45 mg/mL (179.91 mM), Sonication and heating to 60℃ are recommended.
DMSO: 245 mg/mL (979.53 mM), Sonication is recommended.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM3.9981 mL19.9904 mL39.9808 mL199.9040 mL
5 mM0.7996 mL3.9981 mL7.9962 mL39.9808 mL
10 mM0.3998 mL1.9990 mL3.9981 mL19.9904 mL
20 mM0.1999 mL0.9995 mL1.9990 mL9.9952 mL
50 mM0.0800 mL0.3998 mL0.7996 mL3.9981 mL
100 mM0.0400 mL0.1999 mL0.3998 mL1.9990 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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