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Dapoxetine hydrochloride

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Catalog No. T6461Cas No. 129938-20-1
Alias LY-210448 hydrochloride, Dapoxetine HCl

Dapoxetine hydrochloride (LY-210448 hydrochloride) is a selectivity short-acting serotonin reuptake inhibitor, used for the therapy of premature ejaculation.

Dapoxetine hydrochloride

Dapoxetine hydrochloride

🥰Excellent
Purity: 100%
Catalog No. T6461Alias LY-210448 hydrochloride, Dapoxetine HClCas No. 129938-20-1
Dapoxetine hydrochloride (LY-210448 hydrochloride) is a selectivity short-acting serotonin reuptake inhibitor, used for the therapy of premature ejaculation.
Pack SizePriceAvailabilityQuantity
10 mg28 €In Stock
25 mg41 €In Stock
50 mg60 €In Stock
100 mg92 €In Stock
200 mg147 €In Stock
500 mg246 €In Stock
1 mL x 10 mM (in DMSO)56 €In Stock
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Purity:100%
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Product Introduction

Bioactivity
Description
Dapoxetine hydrochloride (LY-210448 hydrochloride) is a selectivity short-acting serotonin reuptake inhibitor, used for the therapy of premature ejaculation.
Kinase Assay
PKA enzyme activity: cAMP-dependent protein kinase activity is assayed in a reaction mixture containing, in a final volume of 0.2 mL, 50 mM Tris-HC1 (pH 7.0), 10 mM magnesium acetate, 2 mM EGTA, 1 μM cAMP or absence of cAMP, 3.3-20 μM [γ-32P]ATP (4 × 105 cpm), 0.5 μg of the enzyme, 100 μg of histone H2B, and each compound, as indicated.
AliasLY-210448 hydrochloride, Dapoxetine HCl
Chemical Properties
Molecular Weight341.87
FormulaC21H23NO·HCl
Cas No.129938-20-1
SmilesCl.CN(C)[C@@H](CCOc1cccc2ccccc12)c1ccccc1
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 25.6 mg/mL (75 mM)
DMSO: 50 mg/mL (146.25 mM)
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM2.9251 mL14.6254 mL29.2509 mL146.2544 mL
5 mM0.5850 mL2.9251 mL5.8502 mL29.2509 mL
10 mM0.2925 mL1.4625 mL2.9251 mL14.6254 mL
20 mM0.1463 mL0.7313 mL1.4625 mL7.3127 mL
50 mM0.0585 mL0.2925 mL0.5850 mL2.9251 mL
DMSO
1mg5mg10mg50mg
100 mM0.0293 mL0.1463 mL0.2925 mL1.4625 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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