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Serotonin hydrochloride

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Catalog No. T2209Cas No. 153-98-0
Alias Serotonin HCl, 5-Hydroxytryptamine hydrochloride, 5-HT hydrochloride, 5-HT HCl

Serotonin hydrochloride (Serotonin HCl) is an endogenous 5-HT receptor agonist, a monoamine neurotransmitter in the CNS, and a catechol O-methyltransferase (COMT) inhibitor(Ki=44 μM).

Serotonin hydrochloride

Serotonin hydrochloride

🥰Excellent
Purity: 99.93%
Catalog No. T2209Alias Serotonin HCl, 5-Hydroxytryptamine hydrochloride, 5-HT hydrochloride, 5-HT HClCas No. 153-98-0
Serotonin hydrochloride (Serotonin HCl) is an endogenous 5-HT receptor agonist, a monoamine neurotransmitter in the CNS, and a catechol O-methyltransferase (COMT) inhibitor(Ki=44 μM).
Pack SizePriceAvailabilityQuantity
25 mg$30In Stock
50 mg$42In Stock
100 mg$52In Stock
200 mg$72In Stock
1 mL x 10 mM (in DMSO)$47In Stock
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Purity:99.93%
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Product Introduction

Bioactivity
Description
Serotonin hydrochloride (Serotonin HCl) is an endogenous 5-HT receptor agonist, a monoamine neurotransmitter in the CNS, and a catechol O-methyltransferase (COMT) inhibitor(Ki=44 μM).
Targets&IC50
COMT:44 μM(Ki)
In vivo
The role of serotonin in the regulation of larval Aedes aegypti hemolymph composition is investigated in vivo using two reuptake inhibitors (SSRIs), alaproclate HCl and 6-nitroquipazine maleate, and the receptor antagonist methiothepin mesylate. [1]
AliasSerotonin HCl, 5-Hydroxytryptamine hydrochloride, 5-HT hydrochloride, 5-HT HCl
Chemical Properties
Molecular Weight212.676
FormulaC10H13ClN2O
Cas No.153-98-0
SmilesCl.NCCc1c[nH]c2ccc(O)cc12
Relative Density.no data available
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 21.3 mg/mL (100 mM)
DMSO: 50 mg/mL (235.1 mM)
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM4.7020 mL23.5099 mL47.0199 mL235.0994 mL
5 mM0.9404 mL4.7020 mL9.4040 mL47.0199 mL
10 mM0.4702 mL2.3510 mL4.7020 mL23.5099 mL
20 mM0.2351 mL1.1755 mL2.3510 mL11.7550 mL
50 mM0.0940 mL0.4702 mL0.9404 mL4.7020 mL
100 mM0.0470 mL0.2351 mL0.4702 mL2.3510 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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