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Alverine citrate

🥰Excellent
Catalog No. T0428Cas No. 5560-59-8
Alias NSC 35459

Alverine citrate (NSC 35459) is utilized in functional gastrointestinal disorders.

Alverine citrate

Alverine citrate

🥰Excellent
Purity: 100%
Catalog No. T0428Alias NSC 35459Cas No. 5560-59-8
Alverine citrate (NSC 35459) is utilized in functional gastrointestinal disorders.
Pack SizePriceAvailabilityQuantity
500 mg$41In Stock
1 g$74In Stock
1 mL x 10 mM (in DMSO)$45In Stock
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Purity:100%
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Product Introduction

Bioactivity
Description
Alverine citrate (NSC 35459) is utilized in functional gastrointestinal disorders.
Targets&IC50
5-HT1A:101 nM
In vivo
Alverine citrate can inhibit calcium-dependent or independent excitability in neurons, as well as directly inactivate L-type calcium channels in smooth muscle cells.
AliasNSC 35459
Chemical Properties
Molecular Weight473.57
FormulaC26H35NO7
Cas No.5560-59-8
SmilesOC(=O)CC(O)(CC(O)=O)C(O)=O.CCN(CCCc1ccccc1)CCCc1ccccc1
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 55 mg/mL (116.14 mM)
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1116 mL10.5581 mL21.1162 mL105.5810 mL
5 mM0.4223 mL2.1116 mL4.2232 mL21.1162 mL
10 mM0.2112 mL1.0558 mL2.1116 mL10.5581 mL
20 mM0.1056 mL0.5279 mL1.0558 mL5.2791 mL
50 mM0.0422 mL0.2112 mL0.4223 mL2.1116 mL
100 mM0.0211 mL0.1056 mL0.2112 mL1.0558 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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