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TargetMol | Compound Library

Serotonin Receptor-Targeted Compound Library

Catalog No. L2800

Serotonin or 5-hydroxytryptamine (5-HT Receptor) is a monoamine neurotransmitter, derivative from the amino acid tryptophan, and mainly located in the enterochromaffin cells in the GI tract and central nervous system (CNS). It has a popular image as a contributor to feelings of well-being and happiness, though its actual biological function is complex and multifaceted, modulating cognition, reward, learning, memory, and numerous physiological processes. Serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in the central and peripheral nervous systems. They can be divided into 7 families of G protein-coupled receptors except for the 5-HT3 receptor, a ligand-gated ion channel, which activate an intracellular second messenger cascade to produce an excitatory or inhibitory response. They mediate both excitatory and inhibitory neurotransmission, influencing various biological and neurological processes. The serotonin receptors are the target of a variety of pharmaceutical and recreational drugs, including many antidepressants, antipsychotics, anorectics, antiemetics, gastroprokinetic agents, antimigraine agents, hallucinogens, and entactogens. The Serotonin (5-HT) Compound Library by TargetMol, collecting 424 small chemicals targeting serotonin receptors, can be used for high throughput screening and high content screening, and drug discovery in neurological disorders.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L2800

Serotonin Receptor-Targeted Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 424 compounds targeting serotonin receptors for high throughput screening and high content screening;
  • Targets include serotonin receptors: 5-HT1, 5-HT2, 5-HT3, 5-HT4, 5-HT6, 5-HT7, etc;
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage | TargetMol Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

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Targetmol Compound Libraries
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Library Customization | TargetMol Library Composition

5-HT Receptor
Dopamine Receptor
Adrenergic Receptor
Histamine Receptor
AChR
Serotonin Transporter
Norepinephrine
Autophagy
Endogenous Metabolite
Potassium Channel
Antibacterial
Apoptosis
Sodium Channel
Sigma receptor
MAO
P2X Receptor
Opioid Receptor
HER
Transferase
Calcium Channel
Drug Metabolite
Cholinesterase (ChE)
GABA Receptor
PKA
Caspase
TRP/TRPV Channel
Reactive Oxygen Species
GluR
Cytochromes P450
CaMK
EGFR
Influenza Virus
NO Synthase
Melanin-concentrating Hormone Receptor (MCHR)
NOS
Histone Methyltransferase
p38 MAPK
Dehydrogenase
Ferroptosis
Adenosine Receptor
Na+/Ca2+ Exchanger
DYRK
Phosphatase
Virus Protease
Melatonin Receptor
OCT
MRP
PARP
Parasite
PKC
iGluR
PDE
GRK
MT Receptor
GlyT
ROS
Stearoyl-CoA Desaturase (SCD)
IL Receptor
CCR
TGF-beta/Smad
P-gp
Prostaglandin Receptor
Trk receptor
Bcl-2 Family
transporter
GST
Beta Amyloid
GPR
Phospholipase
Hydroxylase
FGFR
Anti-infection

Keywords