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Aminoguanidine hydrochloride
Catalog No. T0358Cas No. 1937-19-5
Alias Pimagedine hydrochloride, Pimagedine, Imino semicarbazide, Hydrazinecarboximidamide, Guanyl hydrazine, CP-12009-18 tartrate
Aminoguanidine hydrochloride (Hydrazinecarboximidamide) is a diamine oxidase and NO synthase inhibitor, used in the treatment of diabetic nephropathy.
Aminoguanidine hydrochloride
Catalog No. T0358Alias Pimagedine hydrochloride, Pimagedine, Imino semicarbazide, Hydrazinecarboximidamide, Guanyl hydrazine, CP-12009-18 tartrateCas No. 1937-19-5
Aminoguanidine hydrochloride (Hydrazinecarboximidamide) is a diamine oxidase and NO synthase inhibitor, used in the treatment of diabetic nephropathy.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 mg | $36 | In Stock | |
| 100 mg | $50 | In Stock | |
| 200 mg | $75 | In Stock | |
| 500 mg | $119 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $50 | In Stock |
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Purity:100%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Aminoguanidine hydrochloride (Hydrazinecarboximidamide) is a diamine oxidase and NO synthase inhibitor, used in the treatment of diabetic nephropathy. |
| In vivo | Aminoguanidine ameliorates neonatal hypoxic-ischemic brain damage and that temporal profiles of NO correlated with the neuroprotective effect of aminoguanidine. Neuroprotection by AG is attributable to suppression of NO produced by iNOS after the end of the hypoxic period, during the reoxygenation phase. The half-life of AG is estimated to be between 6 and 8 h in vivo and approximately 4.4 h in human with normal renal function.AG is also an inhibitor of the formation of advanced glycation end products. Systematically administered advanced glycation end product–modified BSA increases cerebral infarct size in an adult rat, which is attenuated by AG[2]. |
| Alias | Pimagedine hydrochloride, Pimagedine, Imino semicarbazide, Hydrazinecarboximidamide, Guanyl hydrazine, CP-12009-18 tartrate |
| Molecular Weight | 110.55 |
| Formula | CH6N4·HCl |
| Cas No. | 1937-19-5 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL (452.28 mM)  Ethanol: < 1 mg/mL (insoluble or slightly soluble) H2O: 20 mg/mL (180.9 mM) | |||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
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