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Noraramtide
Catalog No. TP2750Cas No. 2580150-96-3
Alias BHV-1100
Noraramtide (BHV-1100) is an antibody recruiting molecule that specifically binds to the CD38 molecule to recruit natural killer (NK) cells. This interaction enhances the NK cells' ability to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while preventing mutual NK cell destruction. Noraramtide is utilized in research on autologous cancer immunotherapy.
Noraramtide
Noraramtide
Catalog No. TP2750Alias BHV-1100Cas No. 2580150-96-3
Noraramtide (BHV-1100) is an antibody recruiting molecule that specifically binds to the CD38 molecule to recruit natural killer (NK) cells. This interaction enhances the NK cells' ability to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while preventing mutual NK cell destruction. Noraramtide is utilized in research on autologous cancer immunotherapy.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | Inquiry | Backorder | |
| 50 mg | Inquiry | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Noraramtide (BHV-1100) is an antibody recruiting molecule that specifically binds to the CD38 molecule to recruit natural killer (NK) cells. This interaction enhances the NK cells' ability to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while preventing mutual NK cell destruction. Noraramtide is utilized in research on autologous cancer immunotherapy. |
| Alias | BHV-1100 |
| Molecular Weight | 4633.11 |
| Formula | C210H300N48O65S3 |
| Cas No. | 2580150-96-3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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