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γ-1-MSH, amide acetate (72629-65-3 free base)

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Catalog No. TP1002L
Alias γ-1-MSH, amide acetate

γ-1-MSH, amide acetate (72629-65-3 free base), a putative hormone in the N-terminal region of the ACTH/beta- endorphin (beta-EP) precursor protein, was studied by RIA with an antiserum against gamma 3-MSH in ACTH-producing mouse pituitary tumor cells, AtT-20/D16v.

γ-1-MSH, amide acetate (72629-65-3 free base)

γ-1-MSH, amide acetate (72629-65-3 free base)

🥰Excellent
Purity: 100%
Catalog No. TP1002LAlias γ-1-MSH, amide acetate
γ-1-MSH, amide acetate (72629-65-3 free base), a putative hormone in the N-terminal region of the ACTH/beta- endorphin (beta-EP) precursor protein, was studied by RIA with an antiserum against gamma 3-MSH in ACTH-producing mouse pituitary tumor cells, AtT-20/D16v.
Pack SizePriceAvailabilityQuantity
1 mg$133In Stock
5 mg$302In Stock
10 mg$453In Stock
25 mg$747In Stock
50 mg$1,050In Stock
100 mg$1,420In Stock
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Purity:100%
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Product Introduction

Bioactivity
Description
γ-1-MSH, amide acetate (72629-65-3 free base), a putative hormone in the N-terminal region of the ACTH/beta- endorphin (beta-EP) precursor protein, was studied by RIA with an antiserum against gamma 3-MSH in ACTH-producing mouse pituitary tumor cells, AtT-20/D16v.
In vitro
γ-Melanocyte Stimulating Hormone (γ-MSH) regulates a multitude of metabolic functions including energy homeostasis, food intake, sodium (Na+) balance, and blood pressure regulation. γ-MSH is processed from the precursor hormone pro-opio-melanocortin (POMC) in the pituitary gland, where component peptides are released into the cerebral spinal fluid and systemic circulation. The natural receptor for γ-MSH is the melanocortin receptor 3 (MC3-R), a G-protein-coupled receptor that activates adenylate cyclase and is expressed in brain (hypothalamus, cortex, and thalamus), gut, placenta, and kidney. γ-MSH regulates Na+ balance by inducing urinary Na+ excretion (natriuresis) under conditions of high dietary salt intake[1].
Aliasγ-1-MSH, amide acetate
Chemical Properties
Molecular Weight1572.81
FormulaC74H101N21O16S
SmilesO=C(N[C@@H](CC(O)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N)=O)CC1=CC=CC=C1)=O)=O)[C@@H](NC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@@H](NC(CNC([C@H](CCSC)NC([C@H](C(C)C)NC([C@@H](N)CC2=CC=C(O)C=C2)=O)=O)=O)=O)CC3=CNC=N3)=O)CC4=CC=CC=C4)=O)=O)CC5=CNC6=C5C=CC=C6.CC(O)=O
Relative Density.no data available
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 10 mM
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM0.6358 mL3.1790 mL6.3580 mL31.7902 mL
5 mM0.1272 mL0.6358 mL1.2716 mL6.3580 mL
10 mM0.0636 mL0.3179 mL0.6358 mL3.1790 mL

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