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[D-Pro4,D-Trp7,9] Substance P (4-11)
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Catalog No. T83495Cas No. 81039-85-2
[D-Pro4,D-Trp7,9] Substance P (4-11) acts as a potent Substance P antagonist, significantly reducing plasma aldosterone (ALDO) concentrations[1].
![[D-Pro4,D-Trp7,9] Substance P (4-11)](/group3/M00/02/CF/CgoaEWY7OPSEAOb5AAAAAL1QWWE045.png)
[D-Pro4,D-Trp7,9] Substance P (4-11)
😃Good
Catalog No. T83495Cas No. 81039-85-2
[D-Pro4,D-Trp7,9] Substance P (4-11) acts as a potent Substance P antagonist, significantly reducing plasma aldosterone (ALDO) concentrations[1].
| Pack Size | Price | Availability | Quantity |
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| 5 mg | Inquiry | Backorder | |
| 50 mg | Inquiry | Backorder |
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Chemical Properties
| Description | [D-Pro4,D-Trp7,9] Substance P (4-11) acts as a potent Substance P antagonist, significantly reducing plasma aldosterone (ALDO) concentrations[1]. |
| In vivo | [D-Pro4, D-Trp7,9] Substance P (4-11) antagonizes the hypotensive and vasodilatory responses to Substance P in anesthetized rats and the perfused rabbit heart. Additionally, it inhibits Substance P-induced relaxation in noradrenaline-contracted dog carotid arteries and suppresses stimulatory effects in the guinea pig ileum and trachea [1]. When administered intraperitoneally at 0.3 nM/K/min for 7 days, it significantly reduces plasma aldosterone levels and induces atrophy in the zona glomerulosa and its parenchymal cells of the adrenal gland [2]. |
| Molecular Weight | 1134.35 |
| Formula | C57H75N13O10S |
| Cas No. | 81039-85-2 |
Storage & Solubility Information
| Storage | keep away from moisture | Shipping with blue ice. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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