Shopping Cart
- Remove All
- Your shopping cart is currently empty
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $82 | In Stock | |
5 mg | $333 | In Stock | |
10 mg | $470 | In Stock | |
25 mg | $732 | In Stock | |
50 mg | $990 | In Stock | |
100 mg | $1,330 | In Stock | |
200 mg | $1,780 | In Stock |
Description | CALP3 acetate is a potent Ca2+ channel blocker that activates EF hand motifs of Ca2+-binding proteins. CALP3 acetate can functionally mimic increased [Ca2+]i by modulating the activity of Calmodulin (CaM), Ca2+ channels and pumps. |
In vitro | CALP3 inhibits glutamate caused a large sustained increase in [Ca2+]i in a dose-dependent manner (IC50=37.25 μM) in Fura-2-loaded neuronal cultures. CALP3 inhibits glutamate-induced cytotoxicity in a dose-dependent manner (IC50=50.97 μM) in cultured rat neocortical neurons. CALP3 causes dose-dependent inhibition of apoptosis (IC50=33.41 μM). CALP3 (100 μM) inhibits apoptosis induced by HIV gp120 and SAg in Human T cells. CALP3 (100?μM; 15?min pretreatment) reduces gossypol-induced necrosis and increases the fraction of live cells[1][2]. |
Molecular Weight | 941.12 |
Formula | C46H72N10O11 |
Cas No. |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.