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Bz-Nle-Lys-Arg-Arg-AMC

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Catalog No. T37870Cas No. 863975-32-0

Substrate for dengue virus NS2B-NS3 and yellow fever virus NS3 protease. The kcat/Km value of Bz-NleKRR-AMC for the dengue virus type 4 (DEN4) enzyme is > 800 fold higher than that of Boc-Gly-Arg-Arg-AMC, a widely used NS3 substrate (kcat = 2.9 s 1, Km = 8.6 μM for DEN4). For yellow fever virus NS3 protease the kcat value was 0.111 s 1, the Km value 14.6 μM.

Bz-Nle-Lys-Arg-Arg-AMC

Bz-Nle-Lys-Arg-Arg-AMC

😃Good
Catalog No. T37870Cas No. 863975-32-0
Substrate for dengue virus NS2B-NS3 and yellow fever virus NS3 protease. The kcat/Km value of Bz-NleKRR-AMC for the dengue virus type 4 (DEN4) enzyme is > 800 fold higher than that of Boc-Gly-Arg-Arg-AMC, a widely used NS3 substrate (kcat = 2.9 s 1, Km = 8.6 μM for DEN4). For yellow fever virus NS3 protease the kcat value was 0.111 s 1, the Km value 14.6 μM.
Pack SizePriceAvailabilityQuantity
1 mg$7835 days
5 mg$34835 days
10 mg$59535 days
25 mg$1,33035 days
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Product Introduction

Bioactivity
Description
Substrate for dengue virus NS2B-NS3 and yellow fever virus NS3 protease. The kcat/Km value of Bz-NleKRR-AMC for the dengue virus type 4 (DEN4) enzyme is > 800 fold higher than that of Boc-Gly-Arg-Arg-AMC, a widely used NS3 substrate (kcat = 2.9 s 1, Km = 8.6 μM for DEN4). For yellow fever virus NS3 protease the kcat value was 0.111 s 1, the Km value 14.6 μM.
Chemical Properties
Molecular Weight833.008
FormulaC41H60N12O7
Cas No.863975-32-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMF: 30 mg/mL
DMSO:PBS (pH 7.2) (1:1): 0.5 mg/mL
Ethanol: 20 mg/mL
DMSO: 30 mg/mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

BzNleLysArgArgAMCBz-Nle-Lys-Arg-Arg-AMCBz Nle Lys Arg Arg AMC
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