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740 Y-P(TFA)

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Catalog No. TQ0003L
Alias PDGFR 740Y-P(TFA), 740YPDGFR(TFA), 740 Y-P(TFA)

740 Y-P(TFA) (740YPDGFR(TFA)) is a potent and cell-permeable activator of PI3K.

740 Y-P(TFA)

740 Y-P(TFA)

😃Good
Catalog No. TQ0003LAlias PDGFR 740Y-P(TFA), 740YPDGFR(TFA), 740 Y-P(TFA)
740 Y-P(TFA) (740YPDGFR(TFA)) is a potent and cell-permeable activator of PI3K.
Pack SizePriceAvailabilityQuantity
1 mg$96Backorder
5 mg$264Backorder
10 mg$369Backorder
25 mg$620Backorder
50 mg$944Backorder
100 mg$1,415Backorder
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Product Introduction

Bioactivity
Description
740 Y-P(TFA) (740YPDGFR(TFA)) is a potent and cell-permeable activator of PI3K.
In vitro
740 Y-P is a synthetic biotinylated peptide. 740 Y-P stimulates mitogenesis at the lowest concentration tested (1 mg/mL). The peptide stimulates mitogenesis in both the presence and absence of serum (0.5%) and in the former instance, a maximal response observed at 50 mg/mL. 740Y-P peptide to stimulate mitogenesis is highly specific and not a general feature of a cell-permeable SH2 domain-binding peptide [1]. 740Y-P is as effective as a growth factor (FGF2) at promoting neuronal cell survival via the established PI 3-kinase-Akt survival cascade. Stimulation of neuronal cell survival by the PDGFR740Y-P peptide is dose-dependent and does not require insulin[2].
AliasPDGFR 740Y-P(TFA), 740YPDGFR(TFA), 740 Y-P(TFA)
Chemical Properties
Relative Density.no data available
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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