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187-1, N-WASP inhibitor

Catalog No. TP1977Cas No. 380488-27-7

Inhibits neural Wiskott-Aldrich syndrome protein (N-WASP) by stabilizing the autoinhibited state of the protein. Blocks phosphatidylinositol 4,5-bisphosphate (PIP2)-stimulated actin assembly (IC50 ~ 2 μM) but does not directly inhibit actin polymerization.

187-1, N-WASP inhibitor

187-1, N-WASP inhibitor

Catalog No. TP1977Cas No. 380488-27-7
Inhibits neural Wiskott-Aldrich syndrome protein (N-WASP) by stabilizing the autoinhibited state of the protein. Blocks phosphatidylinositol 4,5-bisphosphate (PIP2)-stimulated actin assembly (IC50 ~ 2 μM) but does not directly inhibit actin polymerization.
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Product Introduction

Bioactivity
Description
Inhibits neural Wiskott-Aldrich syndrome protein (N-WASP) by stabilizing the autoinhibited state of the protein. Blocks phosphatidylinositol 4,5-bisphosphate (PIP2)-stimulated actin assembly (IC50 ~ 2 μM) but does not directly inhibit actin polymerization
Chemical Properties
Molecular Weight1784.13
FormulaC96H122N18O16
Cas No.380488-27-7
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 2 mg/mL

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Keywords

187 1, N WASP inhibitor187-1, N-WASP inhibitor1871, NWASP inhibitor
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