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Transdermal Peptide Disulfide Acetate

🥰Excellent
Catalog No. TP1033L
Alias Transdermal Peptide Disulfide Acetate (888486-23-5 free base), TD 1 (peptide) acetate

Transdermal Peptide acetate(888486-23-5 free base) (TD 1 (peptide) acetate) is a 11-amino acid peptide, binds toNa+/K+-ATPase beta-subunit (ATP1B1), and mainly interacts with the C-terminus of ATP1B1. Transdermal Peptide can enhance the transdermal delivery of many macromolecules.Transdermal Peptide TD 1 Amide is novel peptide designed to enhance transdermal drug delivery.

Transdermal Peptide Disulfide Acetate

Transdermal Peptide Disulfide Acetate

🥰Excellent
Purity: 99.97%
Catalog No. TP1033LAlias Transdermal Peptide Disulfide Acetate (888486-23-5 free base), TD 1 (peptide) acetate
Transdermal Peptide acetate(888486-23-5 free base) (TD 1 (peptide) acetate) is a 11-amino acid peptide, binds toNa+/K+-ATPase beta-subunit (ATP1B1), and mainly interacts with the C-terminus of ATP1B1. Transdermal Peptide can enhance the transdermal delivery of many macromolecules.Transdermal Peptide TD 1 Amide is novel peptide designed to enhance transdermal drug delivery.
Pack SizePriceAvailabilityQuantity
1 mg74 €In Stock
5 mg162 €In Stock
10 mg249 €In Stock
25 mg451 €In Stock
50 mg660 €In Stock
100 mg938 €In Stock
500 mg1.881 €In Stock
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Purity:99.97%
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Product Introduction

Bioactivity
Description
Transdermal Peptide acetate(888486-23-5 free base) (TD 1 (peptide) acetate) is a 11-amino acid peptide, binds toNa+/K+-ATPase beta-subunit (ATP1B1), and mainly interacts with the C-terminus of ATP1B1. Transdermal Peptide can enhance the transdermal delivery of many macromolecules.Transdermal Peptide TD 1 Amide is novel peptide designed to enhance transdermal drug delivery.
In vitro
In the presence of Transdermal Peptide, because of the specific binding of Transdermal Peptide to ATP1B1, cells will upregulate the level of ATP1B1 to maintain function and structure; as a result, the expression of ATP1B1 increases. However, as time goes on, some Transdermal Peptide molecules may be transported into cells by endocytosis; consequently, the expression of ATP1B1 then decreases. The interaction between Transdermal Peptide and ATP1B1 changes not only the expression of ATP1B1, but also the localization of ATP1B1 and then the structure of the epidermal layer. This interaction can be attenuated by inhibitors or competitors, which would result in the reduced delivery of macromolecular drugs across the skin[1].
AliasTransdermal Peptide Disulfide Acetate (888486-23-5 free base), TD 1 (peptide) acetate
Chemical Properties
Molecular Weight1121.2
FormulaC42H68N14O18S2
SmilesC[C@@H](C(=O)N[C@@H]1CCCC[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](SS(=O)[C@H]2CCCN2C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](NC1=O)CO)CO)CO)CO)CCCCN)CC3=CN=CN3)C(=O)NCC(=O)O)N.CC(=O)O
Relative Density.no data available
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 2.5 mM
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM0.8919 mL4.4595 mL8.9190 mL44.5951 mL

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