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H-Leu-Leu-OMe . HBr
Catalog No. T36879L
Alias H-Leu-Leu-OMe . HBr (16689-14-8 Free base)
H-Leu-Leu-OMe . HBr is a dipeptide condensation product of L-leucine methyl ester generated by human monocytes or polymorphonuclear leukocytes. H-Leu-Leu-OMe . HBr induces endolysosomal pathway stress and selectively eliminates lymphocytes with cytotoxic potential.
H-Leu-Leu-OMe . HBr
Catalog No. T36879LAlias H-Leu-Leu-OMe . HBr (16689-14-8 Free base)
H-Leu-Leu-OMe . HBr is a dipeptide condensation product of L-leucine methyl ester generated by human monocytes or polymorphonuclear leukocytes. H-Leu-Leu-OMe . HBr induces endolysosomal pathway stress and selectively eliminates lymphocytes with cytotoxic potential.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $50 | In Stock | |
| 10 mg | $75 | In Stock | |
| 25 mg | $135 | In Stock | |
| 50 mg | $197 | In Stock | |
| 100 mg | $297 | In Stock | |
| 200 mg | $456 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $74 | In Stock |
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Purity:98.91%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | H-Leu-Leu-OMe . HBr is a dipeptide condensation product of L-leucine methyl ester generated by human monocytes or polymorphonuclear leukocytes. H-Leu-Leu-OMe . HBr induces endolysosomal pathway stress and selectively eliminates lymphocytes with cytotoxic potential. |
| In vitro | H-Leu-Leu-OMe . HBr (10-250 μM; 15 min) is converted to a CCI3COOH-insoluble product by CD4- lymphocytes[1]. H-Leu-Leu-OMe . HBr (1 mM; 0.5-2 h) enhances LRRK2-mediated Rab10 and Rab12 phosphorylation in MEFs and A549 cells[2]. |
| Alias | H-Leu-Leu-OMe . HBr (16689-14-8 Free base) |
| Molecular Weight | 399.32 |
| Formula | C15H31BrN2O5 |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 45 mg/mL (112.69 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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