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TOPBioactivityChemical infoStorage&SolubilityCalculator

[Ala1,3,11,15]-Endothelin

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Catalog No. TP2099Cas No. 121204-87-3

Selective ETB endothelin receptor agonist (IC50 values are 0.33 and 2200 nM for displacing [125I]-ET-1 from ETB and ETA receptors respectively).

[Ala1,3,11,15]-Endothelin

[Ala1,3,11,15]-Endothelin

😃Good
Catalog No. TP2099Cas No. 121204-87-3
Selective ETB endothelin receptor agonist (IC50 values are 0.33 and 2200 nM for displacing [125I]-ET-1 from ETB and ETA receptors respectively).
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Product Introduction

Bioactivity
Description
Selective ETB endothelin receptor agonist (IC50 values are 0.33 and 2200 nM for displacing [125I]-ET-1 from ETB and ETA receptors respectively).
Chemical Properties
Molecular Weight2368
FormulaC109H163N25O32S
Cas No.121204-87-3
Relative Density.1.319 g/cm3 (Predicted)
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 1 mg/mL (0.42 mM), Sonication is recommended.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

[Ala1,3,11,15]Endothelin[Ala-1,3,11,15]-Endothelin[Ala1,3,11,15]-Endothelin[Ala1,3,11,15] Endothelin
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