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Urocortin, human (Human urocortin I) is a 40 amino acid peptide which is closely related to corticotrophin-releasing factor (CRF).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
500 μg | $98 | In Stock | |
1 mg | $163 | In Stock | |
5 mg | $372 | In Stock | |
10 mg | $548 | In Stock | |
25 mg | $869 | In Stock |
Description | Urocortin, human (Human urocortin I) is a 40 amino acid peptide which is closely related to corticotrophin-releasing factor (CRF). |
Targets&IC50 | CRF2α (rat):0.3 nM, CRF1 (human):0.4nM, CRF2β (mouse): 0.5 nM |
In vitro | Urocortin, human, is a selective agonist of the CRF2 receptor, displaying Ki values of 0.4 nM for human CRF1, 0.3 nM for rat CRF2α, and 0.5 nM for mouse CRF2β receptors in cell assays [1]. |
In vivo | Urocortin (0.01 to 10 μg) decreases food intake in both food-deprived and non-deprived rats, with similar effects observed in mice following a 1 μg i.c.v. administration. It is a potent suppressor of ingestive behavior and has the potential to induce anxiogenic behavior[2]. |
Alias | Urocortin (human), Human urocortin I, Human urocortin 1, Human urocortin |
Molecular Weight | 4696.32 |
Formula | C204H337N63O64 |
Cas No. | 176591-49-4 |
Relative Density. | no data available |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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