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OM99-2 TFA

Name: OM99-2 TFA
Brand: TargetMol
SKU: T40165
Price: 34 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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Catalog No. T40165Cas No. 2504147-81-1

Alias OM99-2 TFA

OM99-2 TFA is an eight-residue peptidomimetic compound, functioning as a tight-binding inhibitor of human brain memapsin 2. It exhibits a high affinity for the target with a Ki value of 9.58 nM, making it a promising candidate in the development of BACE1 inhibitors. Due to its potential, OM99-2 presents opportunities for further research in the field of Alzheimer's disease.

OM99-2 TFA

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Catalog No. T40165Alias OM99-2 TFACas No. 2504147-81-1

Pack Size	Price	Availability	Quantity
100 mg	Inquiry	Backorder
500 mg	Inquiry	Backorder

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Product Introduction

Bioactivity

Description	OM99-2 TFA is an eight-residue peptidomimetic compound, functioning as a tight-binding inhibitor of human brain memapsin 2. It exhibits a high affinity for the target with a Ki value of 9.58 nM, making it a promising candidate in the development of BACE1 inhibitors. Due to its potential, OM99-2 presents opportunities for further research in the field of Alzheimer's disease.
Targets&IC50	Memapsin 2:9.58 nM (Ki)
In vitro	Memapsin 2 (BACE), an aspartyl protease also recognized as beta-secretase, plays a crucial role in the generation of the beta-amyloid peptide within the human brain[4].
Alias	OM99-2 TFA

Chemical Properties

Molecular Weight	1007.028
Formula	C₄₃H₆₅F₃N₈O₁₆
Cas No.	2504147-81-1
Relative Density.	no data available

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

OM992 TFAOM-99-2 TFAOM99 2 TFA