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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $148 | In Stock | |
5 mg | $336 | In Stock | |
10 mg | $497 | In Stock | |
25 mg | $793 | In Stock | |
50 mg | $1,130 | In Stock | |
100 mg | $1,520 | In Stock |
Description | Camstatin acetate binds calmodulin and inhibits neuronal nitric oxide synthase. Camstatin acetate is a functionally active 25-residue fragment of the single calmodulin-binding IQ motif of PEP-19. |
In vitro | A truncated Camstatin acetate-in which the IQ motif serine is the only phosphorylatable residue-was screened against 42 different kinases. Truncated Camstatin acetate is selectively phosphorylated by four isoforms of protein kinase C. Treatment of full-length PEP-19 with PKCgamma catalyzes phosphorylation of the same serine residue. Phosphorylation of Camstatin acetate inhibits its binding to calmodulin. Both Camstatin acetate and phospho-Camstatin acetate exist in similar dynamic turn-like conformations[1]. |
Molecular Weight | 2820.21 |
Formula | C124H207N39O36 |
Cas No. |
Storage | keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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