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gp91 ds-tat
Catalog No. T80243Cas No. 329902-61-6
gp91 ds-tat is a NADPH oxidase (NOX2) inhibitor that reduces NOX2 expression.
gp91 ds-tat
Catalog No. T80243Cas No. 329902-61-6
gp91 ds-tat is a NADPH oxidase (NOX2) inhibitor that reduces NOX2 expression.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $48 | In Stock | |
| 5 mg | $148 | 7-10 days |
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Purity:98.27%
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Product Introduction
Bioactivity
Chemical Properties
| Description | gp91 ds-tat is a NADPH oxidase (NOX2) inhibitor that reduces NOX2 expression. |
| In vitro | Using confocal microscopy, Hcy induced formation of NLRP3 inflammasomes as indicated by increased colocalization of inflammasome markers, NLRP3 with ASC, and NLRP3 with caspase-1. Pretreatment with the ROS scavenger, catalase (50 U/ml), or gp91 ds-tat peptide blocked this increase. [1] |
| Molecular Weight | 2452.94 |
| Formula | C98H190N50O22S |
| Cas No. | 329902-61-6 |
Storage & Solubility Information
| Storage | keep away from moisture,store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 80 mg/mL（32.61 mM), Sonication is recommended. H2O: < 0.1 mg/mL (insoluble) | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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