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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $239 | In Stock | |
5 mg | $498 | In Stock | |
10 mg | $725 | In Stock | |
25 mg | $1,130 | In Stock | |
50 mg | $1,520 | In Stock |
Description | Semaglutide Acetate is an agonist of a glucagon-like peptide 1 (GLP-1) receptor and can be used in studies about the treatment of type 2 diabetes. |
In vitro | Semaglutide Acetate is a long-acting GLP-1 analogue with GLP-1 receptor affinity of 0.38 nM[3]. |
In vivo | Semaglutide Acetate improves 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP)-induced motor impairments. Semaglutide Acetate rescues the decrease of tyrosine hydroxylase (TH) levels, reduces lipid peroxidation, inhibits the apoptosis pathway, alleviates the inflammation response, increases autophagy-related protein expression, and protects dopaminergic neurons in the substantia nigra and striatum[2]. In mini-pigs, The plasma half-life of Semaglutide Acetate (i.v.) is 46h and the MRT of Semaglutide Acetate (s.c.) is 63.6h[3]. |
Alias | Semaglutide Acetate(910463-68-2 Free base) |
Molecular Weight | 4174.68 |
Formula | C189H295N45O61 |
Cas No. | 1997361-85-9 |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||
Solubility Information | H2O: <0.05 mg/mL (insoluble) ![]() DMSO: 4.17 mg/mL (1 mM), Sonication and heating are recommended. ![]() | ||||||||||
Solution Preparation Table | |||||||||||
DMSO
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