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Cyclo(Arg-Gly-Asp-D-Phe-Val) TFA

Catalog No. T10920Cas No. 199807-33-5

Arg-Gly-Asp-D-Phe-Val (TFA) has anti-tumor activity and is an inhibitor of integrin αvβ3.

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Pack Size	Price	Availability	Quantity
1 mg	$101	Backorder
5 mg	$312	Backorder

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Product Introduction

Bioactivity

Description	Arg-Gly-Asp-D-Phe-Val (TFA) has anti-tumor activity and is an inhibitor of integrin αvβ3.
In vitro	Loop (Arg-Gly-Asp-D-Phe-Val) (TFA) is an inhibitor of integrin αvβ3. Ring (Arg-Gly-Asp-D-Phe-Val) [c (RGDfV); [35 nM] will induce the destruction of leukemia cell migration and adhesion to osteoblasts in 3D and 2D culture systems, affecting the leukemia cell cycle And induce apoptosis of leukemia cells.

Chemical Properties

Molecular Weight	688.662
Formula	C28H39F3N8O9
Cas No.	199807-33-5

Storage & Solubility Information

Storage

keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Cyclo(Arg-Gly-Asp-D-Phe-Val) TFACyclo(Arg Gly Asp D Phe Val) TFACyclo(ArgGlyAspDPheVal) TFA