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H-Ile-Lys-Val-Ala-Val-OH

🥰Excellent
Catalog No. T76583Cas No. 131167-89-0

H-Ile-Lys-Val-Ala-Val-OH (IKVAV) is a short peptide with a sequence length of 5, present in the extracellular matrix (ECM), on the α-laminin chain. H-Ile-Lys-Val-Ala-Val-OH participates in a variety of life activities, such as promoting cell adhesion, neurite outgrowth, angiogenesis, collagenase IV production and tumor growth. H-Ile-Lys-Val-Ala-Val-OH can induce rapid differentiation of neural progenitor cells into neurons and neurite outgrowth.

H-Ile-Lys-Val-Ala-Val-OH

H-Ile-Lys-Val-Ala-Val-OH

🥰Excellent
Catalog No. T76583Cas No. 131167-89-0
H-Ile-Lys-Val-Ala-Val-OH (IKVAV) is a short peptide with a sequence length of 5, present in the extracellular matrix (ECM), on the α-laminin chain. H-Ile-Lys-Val-Ala-Val-OH participates in a variety of life activities, such as promoting cell adhesion, neurite outgrowth, angiogenesis, collagenase IV production and tumor growth. H-Ile-Lys-Val-Ala-Val-OH can induce rapid differentiation of neural progenitor cells into neurons and neurite outgrowth.
Pack SizePriceAvailabilityQuantity
1 mg$40In Stock
5 mg$123In Stock
10 mg$179In Stock
25 mg$293In Stock
50 mg$445In Stock
100 mg$655In Stock
200 mg$933In Stock
500 mg$1,380In Stock
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Product Introduction

Bioactivity
Description
H-Ile-Lys-Val-Ala-Val-OH (IKVAV) is a short peptide with a sequence length of 5, present in the extracellular matrix (ECM), on the α-laminin chain. H-Ile-Lys-Val-Ala-Val-OH participates in a variety of life activities, such as promoting cell adhesion, neurite outgrowth, angiogenesis, collagenase IV production and tumor growth. H-Ile-Lys-Val-Ala-Val-OH can induce rapid differentiation of neural progenitor cells into neurons and neurite outgrowth.
In vitro
Effects of H-Ile-Lys-Val-Ala-Val-OH at various concentrations (0, 0.004, 0.02, 0.1, 0.5 and 2.5 mm) treating BMMSC for different time intervals (0, 24, 48, 72 h) on their viability were determined by CCK‐8 assay. Highest OD value was observed at 72 h when treated with H-Ile-Lys-Val-Ala-Val-OH at 0.5 mm. These results demonstrated that H-Ile-Lys-Val-Ala-Val-OH promoted BMMSC proliferation in a dose‐ and time‐dependent manner. [1]
Chemical Properties
Molecular Weight528.69
FormulaC25H48N6O6
Cas No.131167-89-0
Smiles[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](C(C)C)C(O)=O)=O)C)=O)C(C)C)=O)(NC([C@H]([C@H](CC)C)N)=O)CCCCN
Storage & Solubility Information
Storagekeep away from direct sunlight | store at -20°C | Shipping with blue ice.
Solubility Information
H2O: 80 mg/mL (151.31 mM), Sonication and heating are recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM1.8915 mL9.4573 mL18.9147 mL94.5734 mL
5 mM0.3783 mL1.8915 mL3.7829 mL18.9147 mL
10 mM0.1891 mL0.9457 mL1.8915 mL9.4573 mL
20 mM0.0946 mL0.4729 mL0.9457 mL4.7287 mL
50 mM0.0378 mL0.1891 mL0.3783 mL1.8915 mL
100 mM0.0189 mL0.0946 mL0.1891 mL0.9457 mL

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