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Sp-Uridine-5'-O-(1-thiotriphosphate) sodium

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Catalog No. T83823
Alias Sp-UTP-α-S

Sp-Uridine-5'-O-(1-thiotriphosphate) (Sp-UTP-α-S) acts as a nucleotide agonist for purinergic Y2 (P2Y2) and P2Y4 receptors, efficiently inducing inositol phosphate accumulation in 1321N1 astrocytoma cells that express these receptors, with half-maximal effective concentrations (EC50s) of 14 µM and 81 µM, respectively.

Sp-Uridine-5'-O-(1-thiotriphosphate) sodium

Sp-Uridine-5'-O-(1-thiotriphosphate) sodium

😃Good
Catalog No. T83823Alias Sp-UTP-α-S
Sp-Uridine-5'-O-(1-thiotriphosphate) (Sp-UTP-α-S) acts as a nucleotide agonist for purinergic Y2 (P2Y2) and P2Y4 receptors, efficiently inducing inositol phosphate accumulation in 1321N1 astrocytoma cells that express these receptors, with half-maximal effective concentrations (EC50s) of 14 µM and 81 µM, respectively.
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Product Introduction

Bioactivity
Description
Sp-Uridine-5'-O-(1-thiotriphosphate) (Sp-UTP-α-S) acts as a nucleotide agonist for purinergic Y2 (P2Y2) and P2Y4 receptors, efficiently inducing inositol phosphate accumulation in 1321N1 astrocytoma cells that express these receptors, with half-maximal effective concentrations (EC50s) of 14 µM and 81 µM, respectively.
AliasSp-UTP-α-S
Chemical Properties
Molecular Weight588.14
FormulaC9H11N2O14P3S.4Na
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: Soluble

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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