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[D-Phe2,6, Pro3]-LH-RH is a potent antagonist of luteinizing hormone-releasing hormone (LHRH).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | Inquiry | Backorder | |
50 mg | Inquiry | Backorder |
Description | [D-Phe2,6, Pro3]-LH-RH is a potent antagonist of luteinizing hormone-releasing hormone (LHRH). |
In vitro | The compound [D-Phe2,6, Pro3]-LH-RH demonstrates agonistic activity by binding to gonadotropin-releasing hormone receptors, which stimulates the secretion of luteinizing hormone and follicle-stimulating hormone, thereby increasing the synthesis of testosterone and estrogen. |
In vivo | "[D-Phe2,6, Pro3]-LH-RH (300 mg/monkey, SC, 50 mg/injection; six injections) effectively suppresses spontaneous preovulatory gonadotropin peaks, thereby preventing ovulation in rhesus monkeys [1]. A single dose of [D-Phe2,6, Pro3]-LH-RH (750 μg administered at 12:00 h on proestrus day) achieves 100% inhibition of ovulation in rats [1]." |
Molecular Weight | 1193.35 |
Formula | C59H80N14O13 |
Cas No. | 64789-67-9 |
Storage | keep away from moisture | Shipping with blue ice. |
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