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BT1769

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Catalog No. TP2989

BT1769 is a bicyclic toxin conjugate targeting MT1-MMP (Matrilysin 1 type-MMP) with a KD of 3.35 nM. It is utilized for osteosarcoma research. BT1769 comprises an innovative bicyclic targeting peptide that selectively binds to MT1-MMP, a cytotoxin MMAE, and a dipeptide linker that can be enzymatically cleaved.

BT1769

BT1769

😃Good
Catalog No. TP2989
BT1769 is a bicyclic toxin conjugate targeting MT1-MMP (Matrilysin 1 type-MMP) with a KD of 3.35 nM. It is utilized for osteosarcoma research. BT1769 comprises an innovative bicyclic targeting peptide that selectively binds to MT1-MMP, a cytotoxin MMAE, and a dipeptide linker that can be enzymatically cleaved.
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Product Introduction

Bioactivity
Description
BT1769 is a bicyclic toxin conjugate targeting MT1-MMP (Matrilysin 1 type-MMP) with a KD of 3.35 nM. It is utilized for osteosarcoma research. BT1769 comprises an innovative bicyclic targeting peptide that selectively binds to MT1-MMP, a cytotoxin MMAE, and a dipeptide linker that can be enzymatically cleaved.
Chemical Properties
Molecular Weight3939.45
FormulaC186H269N43O50S
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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