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H-D-Phe-Pip-Arg-pNA dihydrochloride

Catalog No. T40711Cas No. 62354-65-8
Alias S-2238 dihydrochloride, H-D-Phe-Pip-Arg-pNA dihydrochloride

H-D-Phe-Pip-Arg-pNA dihydrochloride (S-2238 dihydrochloride), a chromogenic substrate, mimics the N-terminal fragment of the A alpha chain of fibrinogen, the native substrate of thrombin. Specifically designed for thrombin detection, it is employed for quantifying antithrombin-heparin cofactor (AT-III) and is characterized by its sensitivity, accuracy, and ease of implementation.

H-D-Phe-Pip-Arg-pNA dihydrochloride
Other Forms of H-D-Phe-Pip-Arg-pNA dihydrochloride:
H-D-Phe-Pip-Arg-pNAT3446264815-81-2
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H-D-Phe-Pip-Arg-pNA dihydrochloride

Purity: 99.47%
Catalog No. T40711Alias S-2238 dihydrochloride, H-D-Phe-Pip-Arg-pNA dihydrochlorideCas No. 62354-65-8
H-D-Phe-Pip-Arg-pNA dihydrochloride (S-2238 dihydrochloride), a chromogenic substrate, mimics the N-terminal fragment of the A alpha chain of fibrinogen, the native substrate of thrombin. Specifically designed for thrombin detection, it is employed for quantifying antithrombin-heparin cofactor (AT-III) and is characterized by its sensitivity, accuracy, and ease of implementation.
Pack SizePriceAvailabilityQuantity
1 mg$179In Stock
5 mg$365In Stock
10 mg$543In Stock
25 mg$877In Stock
50 mg$1,180In Stock
100 mg$1,620In Stock
1 mL x 10 mM (in DMSO)$689In Stock
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Purity:99.47%
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Product Introduction

Bioactivity
Description
H-D-Phe-Pip-Arg-pNA dihydrochloride (S-2238 dihydrochloride), a chromogenic substrate, mimics the N-terminal fragment of the A alpha chain of fibrinogen, the native substrate of thrombin. Specifically designed for thrombin detection, it is employed for quantifying antithrombin-heparin cofactor (AT-III) and is characterized by its sensitivity, accuracy, and ease of implementation.
AliasS-2238 dihydrochloride, H-D-Phe-Pip-Arg-pNA dihydrochloride
Chemical Properties
Molecular Weight625.55
FormulaC27H38Cl2N8O5
Cas No.62354-65-8
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 125 mg/mL (199.82 mM)
DMSO: 125 mg/mL (199.82 mM), Sonication is recommended.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM1.5986 mL7.9930 mL15.9859 mL79.9297 mL
5 mM0.3197 mL1.5986 mL3.1972 mL15.9859 mL
10 mM0.1599 mL0.7993 mL1.5986 mL7.9930 mL
20 mM0.0799 mL0.3996 mL0.7993 mL3.9965 mL
50 mM0.0320 mL0.1599 mL0.3197 mL1.5986 mL
100 mM0.0160 mL0.0799 mL0.1599 mL0.7993 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

substrateS-2238InhibitorS 2238inhibitS2238 Dihydrochloridefibrinogenantithrombin-heparinAT-IIIS2238HDPhePipArgpNA dihydrochlorideH D Phe Pip Arg pNA dihydrochloridechromogenicH-D-Phe-Pip-Arg-pNA DihydrochloridecofactorthrombinH-D-Phe-Pip-Arg-pNAS 2238 DihydrochlorideS-2238 Dihydrochloride
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