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Myomodulin is a neuropeptide present in molluscs, insects, and gastropods. Within these organisms, myomodulin A specifically occurs in two identified Aplysia neurons: the ARC motor neuron [B16] and the abdominal neuron [L10].
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $59 | Backorder | |
5 mg | $171 | Backorder | |
10 mg | $264 | Backorder | |
25 mg | $475 | Backorder | |
50 mg | $711 | Backorder | |
100 mg | $1,033 | Backorder |
Description | Myomodulin is a neuropeptide present in molluscs, insects, and gastropods. Within these organisms, myomodulin A specifically occurs in two identified Aplysia neurons: the ARC motor neuron [B16] and the abdominal neuron [L10]. |
In vitro | Myomodulin modulates heart interneuron functions by decreasing the period and increasing spike frequency, alongside enhancing hyperpolarization-activated cation currents and inhibiting the electrogenic Na/K pump[1]. It also plays a role in the nervous system of the leech Hirudo medicinalis, by mediating giant glial cell response to Leydig interneuron stimulation, inducing a significant membrane outward current (EC50 approximately 2 μM) and increasing K+ conductance without desensitization or run-down[2]. Additionally, myomodulin affects ion channels across various organisms, including Aplysia, Lymnaea, and Pleurobranchaea, by differentially modulating potassium currents and decreasing Ca2+ current amplitude by 20%[3]. |
Molecular Weight | 846.12 |
Formula | C36H67N11O8S2 |
Cas No. | 110570-93-9 |
Relative Density. | 1.38g/cm3 |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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