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Myomodulin
Catalog No. TP1852Cas No. 110570-93-9
Myomodulin is a neuropeptide present in molluscs, insects, and gastropods. Within these organisms, myomodulin A specifically occurs in two identified Aplysia neurons: the ARC motor neuron [B16] and the abdominal neuron [L10].
Myomodulin
Catalog No. TP1852Cas No. 110570-93-9
Myomodulin is a neuropeptide present in molluscs, insects, and gastropods. Within these organisms, myomodulin A specifically occurs in two identified Aplysia neurons: the ARC motor neuron [B16] and the abdominal neuron [L10].
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $59 | Backorder | |
| 5 mg | $171 | Backorder | |
| 10 mg | $264 | Backorder | |
| 25 mg | $475 | Backorder | |
| 50 mg | $711 | Backorder | |
| 100 mg | $1,033 | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Myomodulin is a neuropeptide present in molluscs, insects, and gastropods. Within these organisms, myomodulin A specifically occurs in two identified Aplysia neurons: the ARC motor neuron [B16] and the abdominal neuron [L10]. |
| In vitro | Myomodulin modulates heart interneuron functions by decreasing the period and increasing spike frequency, alongside enhancing hyperpolarization-activated cation currents and inhibiting the electrogenic Na/K pump[1]. It also plays a role in the nervous system of the leech Hirudo medicinalis, by mediating giant glial cell response to Leydig interneuron stimulation, inducing a significant membrane outward current (EC50 approximately 2 μM) and increasing K+ conductance without desensitization or run-down[2]. Additionally, myomodulin affects ion channels across various organisms, including Aplysia, Lymnaea, and Pleurobranchaea, by differentially modulating potassium currents and decreasing Ca2+ current amplitude by 20%[3]. |
| Molecular Weight | 846.12 |
| Formula | C36H67N11O8S2 |
| Cas No. | 110570-93-9 |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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