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Myomodulin

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Catalog No. TP1852Cas No. 110570-93-9

Myomodulin is a neuropeptide present in molluscs, insects, and gastropods. Within these organisms, myomodulin A specifically occurs in two identified Aplysia neurons: the ARC motor neuron [B16] and the abdominal neuron [L10].

Myomodulin

Myomodulin

😃Good
Catalog No. TP1852Cas No. 110570-93-9
Myomodulin is a neuropeptide present in molluscs, insects, and gastropods. Within these organisms, myomodulin A specifically occurs in two identified Aplysia neurons: the ARC motor neuron [B16] and the abdominal neuron [L10].
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1 mg$59Backorder
5 mg$171Backorder
10 mg$264Backorder
25 mg$475Backorder
50 mg$711Backorder
100 mg$1,033Backorder
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Product Introduction

Bioactivity
Description
Myomodulin is a neuropeptide present in molluscs, insects, and gastropods. Within these organisms, myomodulin A specifically occurs in two identified Aplysia neurons: the ARC motor neuron [B16] and the abdominal neuron [L10].
In vitro
Myomodulin modulates heart interneuron functions by decreasing the period and increasing spike frequency, alongside enhancing hyperpolarization-activated cation currents and inhibiting the electrogenic Na/K pump[1]. It also plays a role in the nervous system of the leech Hirudo medicinalis, by mediating giant glial cell response to Leydig interneuron stimulation, inducing a significant membrane outward current (EC50 approximately 2 μM) and increasing K+ conductance without desensitization or run-down[2]. Additionally, myomodulin affects ion channels across various organisms, including Aplysia, Lymnaea, and Pleurobranchaea, by differentially modulating potassium currents and decreasing Ca2+ current amplitude by 20%[3].
Chemical Properties
Molecular Weight846.12
FormulaC36H67N11O8S2
Cas No.110570-93-9
Relative Density.1.38g/cm3
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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