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Orexin A (human, rat, mouse) acetate (Hypocretin-1) is an excitatory neuropeptide with analgesic properties. It activates Orexin-1 (OX1R) and Orexin-2 (OX2R) receptors, used for studying neurodegenerative diseases.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $196 | In Stock | |
5 mg | $370 | In Stock | |
10 mg | $445 | In Stock | |
25 mg | $835 | In Stock |
Description | Orexin A (human, rat, mouse) acetate (Hypocretin-1) is an excitatory neuropeptide with analgesic properties. It activates Orexin-1 (OX1R) and Orexin-2 (OX2R) receptors, used for studying neurodegenerative diseases. |
In vitro | Orexin A (human, rat, mouse) acetate (0.1, 1, 10, 100 nM, 24h) increased the expression of BDNF in SH-SY5Y human dopaminergic neuroblastoma cells. [1] Orexin A (human, rat, mouse) acetate (5μM) therapy alleviated the decrease in the number of MC3T3-E1 cells and OCN expression induced by chronic intermittent hypoxia (CIH) by combining with OX1R. [2] |
In vivo | Orexin A (human, rat, mouse) acetate(300 ng/ mouse, injected into the brain) significantly improved spatial learning and memory impairment in MPTP-induced Parkinson's disease mouse models. [1] Orexin A (human, rat, mouse) acetate treatment improved bone formation in CIH mice. [2] |
Alias | Hypocretin-1 (human, rat, mouse) acetate |
Molecular Weight | 3621.15 |
Formula | C154H247N47O46S4 |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
Solubility Information | H2O: 40 mg/mL (11.05 mM), Sonication is recommended. | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
H2O
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