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TCS 1102

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Purity:99.76%

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COA HPLC HNMR

TCS 1102

Catalog No. T2710Cas No. 916141-36-1

TCS 1102 is an effective, dual orexin receptor antagonist (Ki: 0.2/3 nM for OX2/1 receptors).

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Pack Size	Price	Availability
5 mg	$57	In Stock
10 mg	$90	In Stock
25 mg	$176	In Stock
50 mg	$323	In Stock
100 mg	$453	In Stock
500 mg	$1,050	In Stock
1 mL x 10 mM (in DMSO)	$61	In Stock

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Product Introduction

Bioactivity

Description	TCS 1102 is an effective, dual orexin receptor antagonist (Ki: 0.2/3 nM for OX2/1 receptors).
Alias	DORA-1

Chemical Properties

Molecular Weight	470.59
Formula	C27H26N4O2S
Cas No.	916141-36-1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 50 mg/mL (106.25 mM)

Ethanol: 100 mM

Solution Preparation Table

DMSO/Ethanol

	1mg	5mg	10mg	50mg
1 mM	2.1250 mL	10.6250 mL	21.2499 mL	106.2496 mL
5 mM	0.4250 mL	2.1250 mL	4.2500 mL	21.2499 mL
10 mM	0.2125 mL	1.0625 mL	2.1250 mL	10.6250 mL
20 mM	0.1062 mL	0.5312 mL	1.0625 mL	5.3125 mL
50 mM	0.0425 mL	0.2125 mL	0.4250 mL	2.1250 mL
100 mM	0.0212 mL	0.1062 mL	0.2125 mL	1.0625 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc