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(14)
By Target- OX Receptor
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Results for "
hcrt receptor
" in TargetMol Product Catalog- Inhibitor Products14
SB-408124
T6658288150-92-5
SB408124 is a non-peptide antagonist for OX1 receptor with Ki of 57 nM and 27 nM in both whole cell and membrane, respectively, exhibits 50-fold selectivity over OX2 receptor.
- $40
Size
QTY
Filorexant
T160961088991-73-4
Filorexant (MK-6096) is an orally bioavailable effective and selective reversible antagonist of OX1 and OX2 receptor with (Ki <3 nM).
- $48
Size
QTY
MK-1064
T37221207253-08-4
MK-1064 (Urokinase inhibitor 1) is a selective orexin 2 receptor antagonist (2-SORA).
- $64
Size
QTY
IPSU
T55031373765-19-5
IPSU is an antagonist of OX2 receptor. IPSU Exhibits approximately six-fold selectivity for OX2 versus OX1 receptors.
- $34
Size
QTY
Orexin 2 Receptor Agonist
T31771796565-52-0
Orexin 2 Receptor Agonist (OX2R) is an effective (EC50: 23 nM) and OX2R-selective (OX1R/OX2R EC50 ratio: 70) agonist.
- $41
Size
QTY
SB-649868
T5498380899-24-1
SB-649868 (GSK649868) is a potent and selective orally active antagonist of orexin(pKi =9.4 and 9.5 at the OX1 and OX2 receptor, respectively).
- $48
Size
QTY
EMPA
T11186680590-49-2
EMPA is a selective, high-affinity and reversible antagonist of orexin OX2 receptor(human and rat OX2-HEK293 membranes with KD values of 1.1 and 1.4 nM respectively)
- $47
Size
QTY
Almorexant
T2613871224-64-5
Almorexant (ACT 078573) is a potent and competitive dual orexin 1 receptor (OX1)/orexin 2 receptor (OX2) antagonist with Ki values of 1.3 and 0.17 nM for OX1 and OX2, respectively.
- $44
Size
QTY
TCS-OX2-29
T4965372523-75-6
TCS-OX2-29 is a potent and selective OX2 receptor antagonist (IC50: 40 nM). It displays >250-fold selectivity for OX2 over OX1.
- $39
Size
QTY
SB-334867 free base
T6140792173-99-0
SB-334867 free base (SB334867A free base) is a selective orexin-1 (OX1) receptor antagonist.
- $32
Size
QTY
Seltorexant
T12877L1293281-49-8
Seltorexant (JNJ-42847922) crosses the blood-brain barrier and quickly occupies OX2R binding sites in the rat brain. Seltorexant is a high-affinity and selective orexin-2 receptor antagonist (pKi: 8.0 and 8.1 for human and rat OX2R).
- $31
Size
QTY
MK-3697
T19131224846-01-8
MK-3697, an isonicotinamide small molecule, acts as a potent and selective Orexin 2 receptor antagonist (Ki: 0.95 nM).
- $44
Size
QTY
Almorexant hydrochloride
T6155913358-93-7
Almorexant hydrochloride (ACT-078573 hydrochloride) is a potent and competitive dual orexin 1 receptor (OX1)/orexin 2 receptor (OX2) antagonist with Ki values of 1.3 and 0.17 nM for OX1 and OX2, respectively.
- $70
Size
QTY
TCS 1102
T2710916141-36-1
TCS 1102 is an effective, dual orexin receptor antagonist (Ki: 0.2/3 nM for OX2/1 receptors).
- $57
Size
QTY
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Product Comparison
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| Reconstitution |
| Stability & Storage |
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| Research Background |
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