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MK-1064

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Catalog No. T3722Cas No. 1207253-08-4
Alias Urokinase inhibitor 1, MK 1064

MK-1064 (Urokinase inhibitor 1) is a selective orexin 2 receptor antagonist (2-SORA).

MK-1064

MK-1064

🥰Excellent
Purity: 99.88%
Catalog No. T3722Alias Urokinase inhibitor 1, MK 1064Cas No. 1207253-08-4
MK-1064 (Urokinase inhibitor 1) is a selective orexin 2 receptor antagonist (2-SORA).
Pack SizePriceAvailabilityQuantity
1 mg45 €In Stock
5 mg93 €In Stock
10 mg154 €In Stock
25 mg278 €In Stock
50 mg463 €In Stock
100 mg747 €In Stock
1 mL x 10 mM (in DMSO)107 €In Stock
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Purity:99.88%
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Product Introduction

Bioactivity
Description
MK-1064 (Urokinase inhibitor 1) is a selective orexin 2 receptor antagonist (2-SORA).
AliasUrokinase inhibitor 1, MK 1064
Chemical Properties
Molecular Weight461.9
FormulaC24H20ClN5O3
Cas No.1207253-08-4
SmilesCOc1ccc(CNC(=O)c2cc(cnc2-c2ccccn2)-c2cncc(Cl)c2)nc1OC
Relative Density.1.305 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: < 0.1 mg/mL (insoluble)
DMSO: 50 mg/mL (108.25 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1650 mL10.8249 mL21.6497 mL108.2485 mL
5 mM0.4330 mL2.1650 mL4.3299 mL21.6497 mL
10 mM0.2165 mL1.0825 mL2.1650 mL10.8249 mL
20 mM0.1082 mL0.5412 mL1.0825 mL5.4124 mL
50 mM0.0433 mL0.2165 mL0.4330 mL2.1650 mL
100 mM0.0216 mL0.1082 mL0.2165 mL1.0825 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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