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Golotimod

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Purity:99.88%

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COA HNMR HPLC

Golotimod

Catalog No. T11449LCas No. 229305-39-9

Golotimod (SCV 07) is an antimicrobial dipeptide with immunomodulatory activity that significantly improves the efficacy of anti-tuberculosis therapy, induces thymic and splenic cell proliferation, modulates macrophage function, and inhibits STAT3 signaling.Golotimod has been used in the study of recurrent genital Herpes Simplex Virus 2 (HSV-2) infection and oral mucositis.

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Pack Size	Price	Availability
2 mg	$33	In Stock
5 mg	$52	In Stock
10 mg	$81	In Stock
25 mg	$137	In Stock
50 mg	$198	In Stock
100 mg	$289	In Stock

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Product Introduction

Bioactivity

Description	Golotimod (SCV 07) is an antimicrobial dipeptide with immunomodulatory activity that significantly improves the efficacy of anti-tuberculosis therapy, induces thymic and splenic cell proliferation, modulates macrophage function, and inhibits STAT3 signaling.Golotimod has been used in the study of recurrent genital Herpes Simplex Virus 2 (HSV-2) infection and oral mucositis.
In vivo	In female Hartley guinea pigs (250-300 g) infected with HSV-2, Golotimod (100 μg/kg; oral gavage or subcutaneous injection; 5 days) reduced the incidence of lesions from 55% (one week before treatment) to only 18% by oral administration[1].
Alias	Gamma-D-glutamyl-L-tryptophan, SCV 07

Chemical Properties

Molecular Weight	333.34
Formula	C16H19N3O5
Cas No.	229305-39-9

Storage & Solubility Information

Storage

keep away from direct sunlight,keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 100 mg/mL (300.00 mM)

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	2.9999 mL	14.9997 mL	29.9994 mL	149.9970 mL
5 mM	0.6000 mL	2.9999 mL	5.9999 mL	29.9994 mL
10 mM	0.3000 mL	1.5000 mL	2.9999 mL	14.9997 mL
20 mM	0.1500 mL	0.7500 mL	1.5000 mL	7.4999 mL
50 mM	0.0600 mL	0.3000 mL	0.6000 mL	2.9999 mL
100 mM	0.0300 mL	0.1500 mL	0.3000 mL	1.5000 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc