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Golotimod hydrochloride (229305-39-9 free base)
Catalog No. T11449
Alias SCV 07 hydrochloride, Golotimod hydrochloride, Gamma-D-glutamyl-L-tryptophan hydrochloride
Golotimod hydrochloride (SCV 07 hydrochloride) is an immunomodulating peptide with antimicrobial properties. It enhances antituberculosis therapy effectiveness, promotes thymic and splenic cell proliferation, and boosts macrophage functionality. Furthermore, it inhibits STAT3 signaling, thereby modifying the duration and intensity of oral mucositis in animal models subjected to radiation or a combination of radiation and Cisplatin. Additionally, Golotimod hydrochloride has shown potential as a treatment for recurrent genital herpes simplex virus type 2 (HSV-2) [1] [2] [3].
Golotimod hydrochloride (229305-39-9 free base)
Catalog No. T11449Alias SCV 07 hydrochloride, Golotimod hydrochloride, Gamma-D-glutamyl-L-tryptophan hydrochloride
Golotimod hydrochloride (SCV 07 hydrochloride) is an immunomodulating peptide with antimicrobial properties. It enhances antituberculosis therapy effectiveness, promotes thymic and splenic cell proliferation, and boosts macrophage functionality. Furthermore, it inhibits STAT3 signaling, thereby modifying the duration and intensity of oral mucositis in animal models subjected to radiation or a combination of radiation and Cisplatin. Additionally, Golotimod hydrochloride has shown potential as a treatment for recurrent genital herpes simplex virus type 2 (HSV-2) [1] [2] [3].
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $311 | Backorder | |
| 10 mg | $486 | Backorder | |
| 50 mg | $1,454 | Backorder | |
| 100 mg | $1,981 | Backorder | |
| 200 mg | Inquiry | Backorder | |
| 500 mg | Inquiry | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Golotimod hydrochloride (SCV 07 hydrochloride) is an immunomodulating peptide with antimicrobial properties. It enhances antituberculosis therapy effectiveness, promotes thymic and splenic cell proliferation, and boosts macrophage functionality. Furthermore, it inhibits STAT3 signaling, thereby modifying the duration and intensity of oral mucositis in animal models subjected to radiation or a combination of radiation and Cisplatin. Additionally, Golotimod hydrochloride has shown potential as a treatment for recurrent genital herpes simplex virus type 2 (HSV-2) [1] [2] [3]. |
| In vitro | Golotimod hydrochloride is also a potential therapeutic for recurrent genital herpes simplex virus type 2 (HSV-2) [1]. Golotimod inhibits STAT3 signaling and modulates the duration and severity of oral mucositis in animal models that received radiation or a combination of radiation and Cisplatin [2]. |
| Alias | SCV 07 hydrochloride, Golotimod hydrochloride, Gamma-D-glutamyl-L-tryptophan hydrochloride |
| Molecular Weight | 369.8 |
| Formula | C16H20ClN3O5 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | H2O: 125 mg/mL (338.02 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
H2O
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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