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H-Tyr-Phe-OH
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Catalog No. T60935Cas No. 17355-11-2
H-Tyr-Phe-OH (L-Tyrosyl-L-phenylalanine) can be used as a biomarker to distinguish benign thyroid nodules (BTN) from thyroid cancer (TC). It is an orally active Angiotensin-converting enzyme inhibitor with a 48% inhibition rate at 50 μM. Additionally, H-Tyr-Phe-OH exhibits xanthine oxidase inhibitory activity (uric acid lowering) and regulates IL-8 production in neutrophil-like cells [1] [2] [3] [4].
H-Tyr-Phe-OH
😃Good
Catalog No. T60935Cas No. 17355-11-2
H-Tyr-Phe-OH (L-Tyrosyl-L-phenylalanine) can be used as a biomarker to distinguish benign thyroid nodules (BTN) from thyroid cancer (TC). It is an orally active Angiotensin-converting enzyme inhibitor with a 48% inhibition rate at 50 μM. Additionally, H-Tyr-Phe-OH exhibits xanthine oxidase inhibitory activity (uric acid lowering) and regulates IL-8 production in neutrophil-like cells [1] [2] [3] [4].
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 mg | $42 | 7-10 days |
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Chemical Properties
| Description | H-Tyr-Phe-OH (L-Tyrosyl-L-phenylalanine) can be used as a biomarker to distinguish benign thyroid nodules (BTN) from thyroid cancer (TC). It is an orally active Angiotensin-converting enzyme inhibitor with a 48% inhibition rate at 50 μM. Additionally, H-Tyr-Phe-OH exhibits xanthine oxidase inhibitory activity (uric acid lowering) and regulates IL-8 production in neutrophil-like cells [1] [2] [3] [4]. |
| Molecular Weight | 328.36 |
| Formula | C18H20N2O4 |
| Cas No. | 17355-11-2 |
Storage & Solubility Information
| Storage | keep away from moisture | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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