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Ceruletide
🥰Excellent
Catalog No. T14932Cas No. 17650-98-5
Alias FI-6934, Cerulein, Caerulein
Ceruletide is a decapeptide that is a safe and effective cholecystokinin and cholecystokinin receptor agonist with direct spasmodic effects on the gallbladder muscle and bile duct.[1]
Ceruletide
🥰Excellent
Purity: 98.47%
Catalog No. T14932Alias FI-6934, Cerulein, CaeruleinCas No. 17650-98-5
Ceruletide is a decapeptide that is a safe and effective cholecystokinin and cholecystokinin receptor agonist with direct spasmodic effects on the gallbladder muscle and bile duct.[1]
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | 153 € | In Stock | |
| 5 mg | 434 € | In Stock | |
| 10 mg | 604 € | In Stock | |
| 25 mg | 937 € | In Stock | |
| 50 mg | 1.292 € | In Stock | |
| 100 mg | 1.738 € | In Stock |
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XL413 hydrochloride
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Purity:98.47%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Ceruletide is a decapeptide that is a safe and effective cholecystokinin and cholecystokinin receptor agonist with direct spasmodic effects on the gallbladder muscle and bile duct.[1] |
| In vitro | Ceruletide is biologically and chemically identical to the human gastrointestinal hormones cholecystokinin-pancreatin (CCK) and gastrin II；Ceruletide stimulates gallbladder contraction while delaying gastric emptying and inhibiting motility of the proximal duodenum [1]. Ceruletide activates NF-κB/Rel in vitro at high doses (but not physiological doses), which may induce a self-defense gene program before cell damage occurs and may protect pancreatic acinar cells from further damage after secretagogue overstimulation [2]. |
| In vivo | Ceruletide (5-15 ng/kg intravenously) has a significant spasmodic effect on the pylorus in rats[1]; Ceruletide (0.4-0.5 mcg/kg intravenously; 3-4 mcg/kg subcutaneously) causes vomiting and defecation in conscious dogs [3]. |
| Alias | FI-6934, Cerulein, Caerulein |
| Molecular Weight | 1352.4 |
| Formula | C58H73N13O21S2 |
| Cas No. | 17650-98-5 |
| Smiles | CSCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(OS(O)(=O)=O)cc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCC(=O)N1)[C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O |
| Relative Density. | 1.406g/cm3 |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 96 mg/mL (70.98 mM) H2O: 100 mg/mL (73.94 mM) | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO/H2O
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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