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Apoptin-derived peptide

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Catalog No. TP2543Cas No. 2232156-31-7

Apoptin-derived peptide, an antitumor polypeptide, exhibits cytotoxic effects by promoting apoptosis and necrosis in gastric cancer (GC) cells through the modulation of the PI3K / AKT / ARNT signaling pathway. It also impedes both the invasion and migration of cancer cells by inhibiting the expression and phosphorylation of the p85 subunit of PI3K, subsequently suppressing the PI3K / AKT pathway critical to gastric cancer development [1].

Apoptin-derived peptide

Apoptin-derived peptide

😃Good
Catalog No. TP2543Cas No. 2232156-31-7
Apoptin-derived peptide, an antitumor polypeptide, exhibits cytotoxic effects by promoting apoptosis and necrosis in gastric cancer (GC) cells through the modulation of the PI3K / AKT / ARNT signaling pathway. It also impedes both the invasion and migration of cancer cells by inhibiting the expression and phosphorylation of the p85 subunit of PI3K, subsequently suppressing the PI3K / AKT pathway critical to gastric cancer development [1].
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Product Introduction

Bioactivity
Description
Apoptin-derived peptide, an antitumor polypeptide, exhibits cytotoxic effects by promoting apoptosis and necrosis in gastric cancer (GC) cells through the modulation of the PI3K / AKT / ARNT signaling pathway. It also impedes both the invasion and migration of cancer cells by inhibiting the expression and phosphorylation of the p85 subunit of PI3K, subsequently suppressing the PI3K / AKT pathway critical to gastric cancer development [1].
In vitro
TP2543
T85926
T86293
T86717
TN7754
T9901A-054
T9901A-055
Chemical Properties
Molecular Weight5177.33
FormulaC223H417N89O50S
Cas No.2232156-31-7
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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