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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $211 | In Stock | |
5 mg | $815 | In Stock | |
10 mg | $1,223 | In Stock | |
25 mg | $2,197 | In Stock | |
50 mg | $3,297 | In Stock |
Description | VIP(6-28)(human, rat, porcine, bovine) acetate is an antagonist of the actions of exogenous vasoactive intestinal peptide (VIP) receptor on cAMP in the superior cervical ganglion (SCG). |
In vitro | VIP(6-28)(human, rat, porcine, bovine) acetate (10, 30, or 100 μM) reduces the increase in cAMP levels produced by stimulation with 10 μM VIP by 52, 64, or 81%, respectively. Similar results on the ability of VIP(6-28)(human, rat, porcine, bovine) acetate to block VIP-stimulated increases in cAMP levels are obtained in neuron-enriched and non-neuronal cell-enriched dissociated cultures. At any of these concentrations tested, VIP(6-28)(human, rat, porcine, bovine) acetate by itself does not alter cAMP levels. In contrast to its ability to reduce the VIP-stimulated elevation in cAMP levels by 64%, the addition of 30 μM VIP(6-28)(human, rat, porcine, bovine) acetate to the culture medium does not significantly alter cAMP levels measured after stimulation of adult ganglia with either isoproterenol or forskolin (10 μM each)[1]. |
Molecular Weight | 2876.34 |
Formula | C128H211N37O36S |
Cas No. |
Storage | store at low temperature,keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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