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VIP(6-28)(human, rat, porcine, bovine) acetate is an antagonist of the actions of exogenous vasoactive intestinal peptide (VIP) receptor on cAMP in the superior cervical ganglion (SCG).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | 200 € | In Stock | |
5 mg | 774 € | In Stock | |
10 mg | 1.161 € | In Stock | |
25 mg | 2.087 € | In Stock | |
50 mg | 3.132 € | In Stock |
Description | VIP(6-28)(human, rat, porcine, bovine) acetate is an antagonist of the actions of exogenous vasoactive intestinal peptide (VIP) receptor on cAMP in the superior cervical ganglion (SCG). |
In vitro | VIP(6-28)(human, rat, porcine, bovine) acetate (10, 30, or 100 μM) reduces the increase in cAMP levels produced by stimulation with 10 μM VIP by 52, 64, or 81%, respectively. Similar results on the ability of VIP(6-28)(human, rat, porcine, bovine) acetate to block VIP-stimulated increases in cAMP levels are obtained in neuron-enriched and non-neuronal cell-enriched dissociated cultures. At any of these concentrations tested, VIP(6-28)(human, rat, porcine, bovine) acetate by itself does not alter cAMP levels. In contrast to its ability to reduce the VIP-stimulated elevation in cAMP levels by 64%, the addition of 30 μM VIP(6-28)(human, rat, porcine, bovine) acetate to the culture medium does not significantly alter cAMP levels measured after stimulation of adult ganglia with either isoproterenol or forskolin (10 μM each)[1]. |
Molecular Weight | 2876.34 |
Formula | C128H211N37O36S |
Smiles | CC(O)=O.O=C(C[C@@H](C(N)=O)NC([C@H](CC(C)C)NC([C@H]([C@@H](C)CC)NC([C@H](CO)NC([C@@H](NC([C@H](CC(C)C)NC([C@H](CC(C=C1)=CC=C1O)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](C(C)C)NC([C@H](C)NC([C@H](CCSC)NC([C@@H](NC([C@H](CCCCN)NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@H](CCCNC(N)=N)NC([C@@](NC([C@@H](NC([C@H](CC(N)=O)NC([C@@H](NC([C@@](NC([C@@H](N)CC2=CC=CC=C2)=O)([C@@H](C)O)[H])=O)CC(O)=O)=O)=O)CC3=CC=C(C=C3)O)=O)([C@@H](C)O)[H])=O)=O)=O)=O)=O)CCC(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC(N)=O)=O)=O)=O)=O)N |
Relative Density. | 1.31g/cm3 |
Storage | store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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