Shopping Cart
- Remove All
Your shopping cart is currently empty
Margatoxin TFA
😃Good
Catalog No. T80034
Margatoxin TFA, an alpha-KTx scorpion toxin isolated from Centruroides margaritatus venom, is a 39-amino-acid peptide that serves as a high-affinity inhibitor of Kv1.3 (Kd = 11.7 pM). It also inhibits Kv1.2 (Kd = 6.4 pM) and Kv1.1 (Kd = 4.2 nM), making it a valuable tool for ion channel research [1] [2].
Margatoxin TFA
Margatoxin TFA
😃Good
Catalog No. T80034
Margatoxin TFA, an alpha-KTx scorpion toxin isolated from Centruroides margaritatus venom, is a 39-amino-acid peptide that serves as a high-affinity inhibitor of Kv1.3 (Kd = 11.7 pM). It also inhibits Kv1.2 (Kd = 6.4 pM) and Kv1.1 (Kd = 4.2 nM), making it a valuable tool for ion channel research [1] [2].
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | Inquiry | Backorder | |
| 50 mg | Inquiry | Backorder |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "Margatoxin TFA"
Indapamide
Veroxil, Tertensif, Noranat
T149826807-65-8
Indapamide (Noranat) is a non-thiazide sulphonamide diuretic compound, generally used in the treatment of hypertension, as well as decompensated cardiac failure.
Inquiry
Minoxidil sulfate
U-58838, Minoxidil sulphate
T813583701-22-8
Minoxidil sulfate (U-58838) is the active metabolite required to exert the vasodilatory and hair growing effects of minoxidil.
- 29 €
Size
QTY
Hydrochlorothiazide
HCTZ
T144958-93-5
Hydrochlorothiazide (HCTZ) is a Thiazide Diuretic. The physiologic effect of hydrochlorothiazide is by means of Increased Diuresis.
- 45 €
Size
QTY
Ursodeoxycholic acid
Cited
Ursodiol, UDCA
T0700128-13-2
Ursodeoxycholic acid (UDCA) can be used to dissolve gallstones and reduce cholesterol absorption.
- 47 €
Size
QTY
CitedHalothane
Narcotane, Anestan
T0954151-67-7
Halothane (Anestan) is a nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little or no excitement. Analgesia may not be adequate. NITROUS OXIDE is often given concomitantly. Because halothane may not produce sufficient muscle relaxation, supplemental neuromuscular blocking agents may be required.
- 42 €
Size
QTY
Cloperastine hydrochloride
HT-11 hydrochloride
T072314984-68-0
Cloperastine hydrochloride (HT-11 hydrochloride) is a type of flavonoid.
- 29 €
Size
QTY
Tetraethylammonium bromide
TEAB, TEA bromide
T836171-91-0
Tetraethylammonium bromide (TEA bromide) can selectively block potassium channels.
- 27 €
Size
QTY
Butamben
Butyl 4-aminobenzoate
T091694-25-7
Butamben (Butyl 4-aminobenzoate) is a long-duration local anesthetic used for the treatment of chronic pain.
- 29 €
Size
QTY
(±)-Naringenin Cited
Salipurpol, Naringenine, Naringenin
TMS217167604-48-2
(±)-Naringenin (Naringenine) is a natural product. It displays vasorelaxant effect on endothelium-denuded vessels via the activation of BKCa channels in myocytes.
- 42 €
Size
QTY
CitedMinoxidil
U10858
T045138304-91-5
Minoxidil (U10858) is an orally administered vasodilator with hair growth stimulatory and antihypertensive effects.
- 47 €
Size
QTY
Tolbutamide Cited
HLS 831
T105464-77-7
Tolbutamide (HLS 831) is a sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE.
- 38 €
Size
QTY
CitedQuinine sulfate dihydrate
TN48836119-70-6
Quinine sulfate dihydrate plays a major role in potassium channel blockers. It is also used as an antimalarial, anticholinergic, antihypertensive and a hypoglycemic agent. It inhibits mitochondrial ATP-regulated potassium channel. It is also used to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites and to study the toxicity of heme (FP)-complexes.
- 27 €
Size
QTY
Contact us for more batch information
Resource Download
Product Introduction
Bioactivity
Chemical Properties
| Description | Margatoxin TFA, an alpha-KTx scorpion toxin isolated from Centruroides margaritatus venom, is a 39-amino-acid peptide that serves as a high-affinity inhibitor of Kv1.3 (Kd = 11.7 pM). It also inhibits Kv1.2 (Kd = 6.4 pM) and Kv1.1 (Kd = 4.2 nM), making it a valuable tool for ion channel research [1] [2]. |
| In vivo | In 12-week-old C57BL/6J mice, Margatoxin TFA (ip; 1 pmol/g) significantly reduced thioglycollate-induced peritoneal leukocyte migration [2]. |
| Molecular Weight | 4178.95 (free base) |
| Formula | C178H286N52O50S7.xC2HF3O2 |
Storage & Solubility Information
| Storage | keep away from moisture | Shipping with blue ice. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Margatoxin TFA | purchase Margatoxin TFA | Margatoxin TFA cost | order Margatoxin TFA | Margatoxin TFA in vivo | Margatoxin TFA formula | Margatoxin TFA molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.