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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | Inquiry | Backorder | |
50 mg | Inquiry | Backorder |
Description | [D-Ala2] Leu-Enkephalinamide, an enkephalin analog, exhibits significant corneal permeability and analgesic properties, making it suitable for ocular disease research [1] [2]. |
In vitro | [D-Ala2] Leu-Enkephalinamide (MEA) operates as an agonist at opioid receptors, selectively binding to these sites and modulating neurotransmitter release, thereby eliciting analgesic effects. Its activity mimics that of endogenous opioid peptides, primarily affecting mu-type receptors, which play a key role in pain regulation within the central nervous system. |
In vivo | D-Ala2-Leu-enkephalinamide administered subcutaneously (s.c.) demonstrates increased activity in morphine-dependent animals [2]. |
Molecular Weight | 568.66 |
Formula | C29H40N6O6 |
Cas No. | 65189-64-2 |
Storage | keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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