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ERα17p
Catalog No. TP2682Cas No. 938077-77-1
Alias ERα (295-311)
ERα17p (ERα 295-311), the epitope of the CaM binding site located on estrogen receptor α (ER), interacts with calmodulin (CaM) in a calcium-dependent fashion. This peptide is involved in regulating the migration of various cancer cell lines including MCF-7, SK-BR-3, T47D, and MDA-MB-231 via the Rho/ROCK and PI3K/Akt signaling pathways. Additionally, ERα17p plays a role in suppressing proliferation and inducing apoptosis in breast cancer cells, as well as inhibiting tumor growth in mouse models.
ERα17p
Catalog No. TP2682Alias ERα (295-311)Cas No. 938077-77-1
ERα17p (ERα 295-311), the epitope of the CaM binding site located on estrogen receptor α (ER), interacts with calmodulin (CaM) in a calcium-dependent fashion. This peptide is involved in regulating the migration of various cancer cell lines including MCF-7, SK-BR-3, T47D, and MDA-MB-231 via the Rho/ROCK and PI3K/Akt signaling pathways. Additionally, ERα17p plays a role in suppressing proliferation and inducing apoptosis in breast cancer cells, as well as inhibiting tumor growth in mouse models.
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| 50 mg | Inquiry | Backorder |
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Chemical Properties
| Description | ERα17p (ERα 295-311), the epitope of the CaM binding site located on estrogen receptor α (ER), interacts with calmodulin (CaM) in a calcium-dependent fashion. This peptide is involved in regulating the migration of various cancer cell lines including MCF-7, SK-BR-3, T47D, and MDA-MB-231 via the Rho/ROCK and PI3K/Akt signaling pathways. Additionally, ERα17p plays a role in suppressing proliferation and inducing apoptosis in breast cancer cells, as well as inhibiting tumor growth in mouse models. |
| Alias | ERα (295-311) |
| Molecular Weight | 1900.33 |
| Formula | C84H154N24O23S |
| Cas No. | 938077-77-1 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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