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HPV16 E7 (86-93) acetate

HPV16 E7 (86-93) acetate
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HPV16 E7 (86-93) acetate

Catalog No. TP1554L
HPV16 E7 (86-93) acetate is a derived peptide of human leukocyte antigen A2.1 restricted HPV16 E7 with immunogenic property in cervical carcinomas.
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Pack SizePriceAvailabilityQuantity
1 mg$129In Stock
5 mg$265In Stock
10 mg$377In Stock
25 mg$633In Stock
50 mg$883In Stock
100 mg$1,230In Stock
500 mg$2,470In Stock
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Product Introduction

Bioactivity
Description
HPV16 E7 (86-93) acetate is a derived peptide of human leukocyte antigen A2.1 restricted HPV16 E7 with immunogenic property in cervical carcinomas.
In vitro
HPV16 E7 peptide-loaded autologous dendritic cells stimulate a specific cytotoxic CD8+ T-cell response[1]. HPV16 E7 (86-93) acetate specific T cells expand upon in vitro stimulation with cognate peptide-pulsed dendritic cells. HPV16 E7 (86-93) acetate specific T cells are reactive against peptide-pulsed targets. HPV16 E7 (86-93) acetate specific E711-20 T cells are reactive against HPV16 E7 expressing CaSki cell line. Precursor T cells specific for HPV16 E7 (86-93) acetate differentiates into HPV specific effector cells in vitro[2].
In vivo
HPV16 E7 (86-93) acetate in IVS culture has specific T cell expansion without recognizing naturally HPV16 E7 expressing cell line CaSki. HPV16 E7 (86-93) acetate has similar observations in transgenic mice. HPV16 E7 (86-93) acetate induces cytotoxic T lymphocyte responses when loaded on the antigen presenting HLA class I molecules[2].
AliasHPV16 E7 (86-93) acetate(160212-93-1 Free base)
Chemical Properties
Molecular Weight875.08
FormulaC39H70N8O12S
Cas No.
Storage & Solubility Information
Storagekeep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year

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