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HPV16 E7 (86-93) acetate
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Catalog No. TP1554L
Alias HPV16 E7 (86-93) acetate(160212-93-1 Free base)
HPV16 E7 (86-93) acetate is a derived peptide of human leukocyte antigen A2.1 restricted HPV16 E7 with immunogenic property in cervical carcinomas.
HPV16 E7 (86-93) acetate
🥰Excellent
Purity: 96.91%
Catalog No. TP1554LAlias HPV16 E7 (86-93) acetate(160212-93-1 Free base)
HPV16 E7 (86-93) acetate is a derived peptide of human leukocyte antigen A2.1 restricted HPV16 E7 with immunogenic property in cervical carcinomas.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $77 | In Stock | |
| 5 mg | $159 | In Stock | |
| 10 mg | $226 | In Stock | |
| 25 mg | $380 | In Stock | |
| 50 mg | $530 | In Stock | |
| 100 mg | $738 | In Stock | |
| 200 mg | $996 | In Stock |
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Purity:96.91%
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Product Introduction
Bioactivity
Chemical Properties
| Description | HPV16 E7 (86-93) acetate is a derived peptide of human leukocyte antigen A2.1 restricted HPV16 E7 with immunogenic property in cervical carcinomas. |
| In vitro | HPV16 E7 peptide-loaded autologous dendritic cells stimulate a specific cytotoxic CD8+ T-cell response[1]. HPV16 E7 (86-93) acetate specific T cells expand upon in vitro stimulation with cognate peptide-pulsed dendritic cells. HPV16 E7 (86-93) acetate specific T cells are reactive against peptide-pulsed targets. HPV16 E7 (86-93) acetate specific E711-20 T cells are reactive against HPV16 E7 expressing CaSki cell line. Precursor T cells specific for HPV16 E7 (86-93) acetate differentiates into HPV specific effector cells in vitro[2]. |
| In vivo | HPV16 E7 (86-93) acetate in IVS culture has specific T cell expansion without recognizing naturally HPV16 E7 expressing cell line CaSki. HPV16 E7 (86-93) acetate has similar observations in transgenic mice. HPV16 E7 (86-93) acetate induces cytotoxic T lymphocyte responses when loaded on the antigen presenting HLA class I molecules[2]. |
| Alias | HPV16 E7 (86-93) acetate(160212-93-1 Free base) |
| Molecular Weight | 875.08 |
| Formula | C39H70N8O12S |
| Smiles | C[C@@H](O)[C@H](N)C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@@H](CS)C(N1CCC[C@H]1C(N[C@@H]([C@@H](C)CC)C(O)=O)=O)=O)=O)C(C)C)=O)[C@@H](C)CC)=O)=O)CC(C)C)=O.CC(O)=O |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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