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Neurokinin A
Catalog No. TP1008Cas No. 86933-74-6
Alias α-Neurokinin, Substance K, Neuromedin L
Neurokinin A (NKA), formerly known as Substance K, is a neurologically active peptide translated from the pre-protachykinin gene.
Neurokinin A
Catalog No. TP1008Alias α-Neurokinin, Substance K, Neuromedin LCas No. 86933-74-6
Neurokinin A (NKA), formerly known as Substance K, is a neurologically active peptide translated from the pre-protachykinin gene.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $56 | In Stock | |
| 5 mg | $123 | In Stock | |
| 10 mg | $213 | In Stock | |
| 25 mg | $359 | In Stock | |
| 50 mg | $533 | In Stock | |
| 100 mg | $759 | In Stock |
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View MoreInhibitors Related to "Neurokinin A"
Aprepitant
MK-869, MK-0869, L-754030, Aprepitant`
T1743170729-80-3
Aprepitant is a Substance P/Neurokinin-1 Receptor Antagonist. The mechanism of action of aprepitant is as a Neurokinin 1 Antagonist, and Cytochrome P450 3A4 Inhibitor, and Cytochrome P450 2C9 Inducer, and Cytochrome P450 3A4 Inducer.
- $48
Size
QTY
Aprepitant
MK-869, MK-0869, L-754030, Aprepitant`
T1743170729-80-3
Aprepitant is a Substance P/Neurokinin-1 Receptor Antagonist. The mechanism of action of aprepitant is as a Neurokinin 1 Antagonist, and Cytochrome P450 3A4 Inhibitor, and Cytochrome P450 2C9 Inducer, and Cytochrome P450 3A4 Inducer.
- $48
Size
QTY
Aprepitant
MK-869, MK-0869, L-754030, Aprepitant`
T1743170729-80-3
Aprepitant is a Substance P/Neurokinin-1 Receptor Antagonist. The mechanism of action of aprepitant is as a Neurokinin 1 Antagonist, and Cytochrome P450 3A4 Inhibitor, and Cytochrome P450 2C9 Inducer, and Cytochrome P450 3A4 Inducer.
- $48
Size
QTY
Aprepitant
MK-869, MK-0869, L-754030, Aprepitant`
T1743170729-80-3
Aprepitant is a Substance P/Neurokinin-1 Receptor Antagonist. The mechanism of action of aprepitant is as a Neurokinin 1 Antagonist, and Cytochrome P450 3A4 Inhibitor, and Cytochrome P450 2C9 Inducer, and Cytochrome P450 3A4 Inducer.
- $48
Size
QTY
Maropitant
T7209147116-67-4
Maropitant is a selective neurokinin (NK1) receptor antagonist.
- $43
Size
QTY
Befetupitant
Ro67-5930
T14524290296-68-3In house
Befetupitant (Ro67-5930) is a potent and selective tachykinin 1 receptor (NK1R) antagonist for the study of corneal neovascularization.
- $490
Size
QTY
Rolapitant
SCH619734
T3716552292-08-7
Rolapitant (SCH619734) Hydrochloride is the hydrochloride salt form of rolapitant, an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor) antagonist with potential antiemetic activity. Upon oral administration, rolapitant competitively binds to and blocks the activity of the NK1-receptor in the central nervous system, thereby inhibiting the binding of the endogenous ligand, substance P (SP). This may prevent both SP-induced emesis and chemotherapy-induced nausea and vomiting (CINV). The interaction of SP with the NK1-receptor plays a key role in the induction of nausea and vomiting caused by emetogenic cancer chemotherapy. Compared to other NK1-receptor antagonists, rolapitant has both a more rapid onset of action and a much longer half-life.
- $43
Size
QTY
N-Acetyl-L-tryptophan
N-acetyltryptophan
T87891218-34-4
N-Acetyl-L-tryptophan (N-acetyltryptophan) is an inhibitor of neurokinin 1 receptor (NK1-receptor, NK1R).
- $30
Size
QTY
N-Acetyl-L-tryptophan
N-acetyltryptophan
T87891218-34-4
N-Acetyl-L-tryptophan (N-acetyltryptophan) is an inhibitor of neurokinin 1 receptor (NK1-receptor, NK1R).
- $30
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QTY
N-Acetyl-L-tryptophan
N-acetyltryptophan
T87891218-34-4
N-Acetyl-L-tryptophan (N-acetyltryptophan) is an inhibitor of neurokinin 1 receptor (NK1-receptor, NK1R).
- $30
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Purity:100%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Neurokinin A (NKA), formerly known as Substance K, is a neurologically active peptide translated from the pre-protachykinin gene. |
| In vitro | Neurokinin A (Substance K), a peptide neurotransmitter from the tachykinin family, plays a key role as a mediator in human airway and gastrointestinal tissues through its action on the NK-2 receptor, primarily found on smooth muscle cells and linked to a GTP-binding protein. As part of the tachykinin family, known for its involvement in both the central and peripheral nervous systems and its broad tissue presence, Neurokinin A shares a common COOH-terminal structure Phe-X-Gly-Leu-Met-NH with other family members, including well-recognized peers like Substance P. |
| Alias | α-Neurokinin, Substance K, Neuromedin L |
| Molecular Weight | 1133.32 |
| Formula | C50H80N14O14S |
| Cas No. | 86933-74-6 |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | H2O: 100 mg/mL (88.24 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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