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Ac-hMCH(6-16)-NH2 shows non-selective agonist activity towards both MCH-1R and MCH-2R, which are human MCH receptors in the brain. The compound effectively binds to and activates these receptors, with IC 50 values of 0.16 nM and 2.7 nM for MCH-1R and MCH-2R, respectively.
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Description | Ac-hMCH(6-16)-NH2 shows non-selective agonist activity towards both MCH-1R and MCH-2R, which are human MCH receptors in the brain. The compound effectively binds to and activates these receptors, with IC 50 values of 0.16 nM and 2.7 nM for MCH-1R and MCH-2R, respectively. |
In vitro | Ac-hMCH(6-16)-NH2 demonstrates efficacy in activating MCH-1R and MCH-2R receptors, with EC 50 values of 20 nM for MCH-1R and 98 nM for MCH-2R, as measured in an aequorin-based functional assay[1]. |
Alias | Ac-hMCH(6-16)-NH2 |
Molecular Weight | 1394.74 |
Formula | C58H99N21O13S3 |
Cas No. | 1053601-50-5 |
Relative Density. | 1.47 g/cm3 (Predicted) |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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