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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $42 | Backorder | |
5 mg | $91 | Backorder | |
10 mg | $148 | Backorder | |
25 mg | $297 | Backorder | |
50 mg | $448 | Backorder |
Description | Caloxin 2A1 TFA is a peptide inhibitor specifically targeting the extracellular plasma membrane Ca2+-ATPase (PMCA), without influencing the basal activities of Mg2+-ATPase or Na+-K+-ATPase[1]. |
In vitro | Caloxin 2A1 TFA inhibits Ca2+-Mg2+-ATPase in human erythrocyte leaky ghosts, but it does not affect basal Mg2+-ATPase or Na+-K+-ATPase in the ghosts or Ca2+-Mg2+-ATPase in the skeletal muscle sarcoplasmic reticulum. Caloxin 2A1 TFA also inhibits Ca2+-dependent formation of the 140-kDa acid-stable acylphosphate[1].Caloxin 2A1 TFA increases airway smooth muscle cells (ASMCs) apoptosis[2]. |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO: 100 mg/mL (62.79 mM), Sonication is recommended. |
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